When treating Hepatitis B "Big Three Yang", you need to be patient because the treatment course is very long.

A friend left a message to Huazi, asking what to pay attention to when treating hepatitis B "big three positive"? Huazi said that hepatitis B "big three positive" refers to the positive reaction of hepatitis B surface antigen (HBsAg), hepatitis B e antigen (HBeAg), and hepatitis B core antibody (HBcAb) in the "hepatitis B two-pair half" test.

Hepatitis B "big three positive" means that the hepatitis B virus in the body is in the active replication stage and is highly contagious. At this time, the treatment is mainly antiviral treatment, and liver protection treatment is carried out according to the liver function. Patience is required for the treatment of "big three positive" because the treatment course is very long.

1. It is difficult to completely eliminate the hepatitis B virus. The 2017 Global Hepatitis B Report shows that there are more than 90 million people infected with the hepatitis B virus in China. If they cannot receive timely and effective treatment, more than 20% of hepatitis B patients may develop cirrhosis or liver cancer.

Hepatitis B virus is not a virus that develops rapidly. It may take 10 to 20 years for the disease to develop after infection. Many infected people do not have any symptoms and only find out that they are infected during a physical examination.

After the hepatitis B virus infects the human body, it will not cause particularly serious effects on the liver, but it may suddenly activate the human immune system, attacking liver cells infected with the virus but with normal function, causing acute liver damage.

When liver cells are attacked by the immune system or chronically eaten away by viruses, they lose their normal functions and are prone to developing cirrhosis. When the damage persists, it may cause liver cell mutations and induce liver cancer. Studies have shown that 80% of liver cancers are related to hepatitis B.

After infecting the human body, the hepatitis B virus stores its DNA information in the nucleus of liver cells. Even if the human immune system eliminates all viruses outside the cells, the liver cells that store the hepatitis B virus DNA will continue to produce hepatitis B virus, making it difficult to completely eliminate the hepatitis B virus.

2. The course of anti-HBV treatment is very long. The treatment of hepatitis B "big three positive" is mainly to inhibit the replication of the virus, cooperate with the body's own immunity, and use the powerful regeneration function of liver cells to suppress the hepatitis B virus at a lower load, delay the progression of the disease, and avoid the occurrence of cirrhosis and liver cancer.

Entecavir, tenofovir and interferon are the main drugs used to treat hepatitis B virus, and are called the "three musketeers" of anti-hepatitis B virus treatment. Lamivudine and adefovir dipivoxil, which are used to treat AIDS, can also be used to treat hepatitis B.

Each drug has its own contraindications and adverse reactions. The hepatitis B virus may also develop drug resistance, so you should choose the drug under the guidance of a doctor and adjust the drug according to changes in indicators after taking the drug.

It should be noted that anti-HBV drugs cannot kill the virus directly, but inhibit the replication of the virus, allowing the viral load to slowly decrease. Therefore, the course of treatment is very long, at least more than 1 year, and you need to take the medicine consistently and not give up halfway. If you stop taking the medicine without authorization, it may lead to drug resistance and prolong the course of the disease.

3. Pay attention to protecting liver function. People with hepatitis B need to pay attention to liver function, but do not be overly concerned about slight changes in liver function. If liver transaminases (AST, ALT) are slightly elevated, as long as there are no obvious symptoms, it is not recommended to use medication to forcibly lower transaminases.

Because liver protection drugs have no inhibitory effect on viruses, lowering transaminase is only a temporary solution, and liver protection drugs also need to be metabolized by the liver, which will increase the burden on the liver. As long as the viral load decreases, the transaminase will naturally decrease. Therefore, when treating hepatitis B "big three positives", antiviral treatment should be the main focus, and liver protection should be secondary.

To protect the liver, you must avoid behaviors that damage the liver. You must quit smoking and drinking, don't stay up late, don't eat moldy food, eat a light diet, and don't eat spicy or irritating foods. You must pay attention to balanced nutrition and take in enough protein, vitamins, carbohydrates, and fats to help the liver recover.

To sum up, it is difficult to completely eliminate hepatitis B infection, but taking medication according to the course of treatment under the guidance of a doctor can suppress the hepatitis B virus for a long time and turn the "big three positives" negative. However, the course of treatment is long, and it usually takes 1 to 2 years of continuous medication to see the effect. Some people need longer. Pay attention to taking medication regularly and do not stop taking medication without authorization. If you have any questions about medication, please consult a doctor or pharmacist. I am pharmacist Huazi. Welcome to follow me and share more health knowledge.