Are Lolamine drugs used to lower blood pressure or treat heart disease? They can do both.

Several friends came to consult Huazi about the issues of Lolamine drugs. A young friend asked about the effect of Lolamine drugs on hypertension; an elderly friend asked about the effect of Lolamine drugs on coronary heart disease; and another friend asked, "I heard that the number of heartbeats in a person's life is fixed, and whoever finishes beating first dies first. Lolamine drugs can slow down the heart rate, so after taking them, can people live longer?"

Huazi replied that Lol drugs can treat both high blood pressure and coronary heart disease, and can achieve the best of both worlds. Controlling the disease well can prolong the patient's life span, but human life span has nothing to do with the speed of the heart rate.

1. What are Lol drugs? Lol drugs are called beta-blockers in pharmacology. Common drugs include propranolol, atenolol, metoprolol, bisoprolol, carvedilol, etc. Their main function is to reduce cardiac excitability, reduce myocardial contractility, slow down heart rate, reduce cardiac output, and lower blood pressure by inhibiting the beta-1 receptors on the heart.

Lolamine drugs can also inhibit the β1 receptors of the juxtaglomerular cells, reducing the release of renin, thereby reducing the angiotensin converted by renin, and also lowering blood pressure.

2. Uses of Lolamine drugs 1. Treatment of hypertension: Lolamine drugs are first-line antihypertensive drugs and can be used alone or in combination with other antihypertensive drugs. The common cause of hypertension in young and middle-aged people is excessive excitement of the sympathetic nerves caused by mental tension, anxiety, and excessive stress. While blood pressure rises, it is also accompanied by symptoms of too fast heart rate. Lolamine drugs can inhibit the excitement of cardiac nerves and slow down the heart rate, so they are suitable for young and middle-aged people with hypertension.

2. Treatment of coronary heart disease: Patients with coronary heart disease experience symptoms of angina pectoris due to myocardial insufficiency and myocardial hypoxia caused by coronary artery stenosis. Lolamine drugs can treat angina pectoris by inhibiting cardiac excitement, weakening cardiac movement, and reducing cardiac oxygen consumption. Long-term use of Lolamine drugs can significantly reduce cardiovascular events and mortality.

3. Treatment of tachycardia: Some people have high cardiac excitability, increased autonomy, or ectopic rhythm points, which cause premature beats and tachycardia. If the heart rate exceeds 80 at rest, many people will feel flustered and have palpitations. Lolamine drugs can be used to inhibit cardiac excitability, reduce heart rate, and eliminate the symptoms of palpitations.

4. Treatment of chronic heart failure: The mechanism of Lolamine drugs in treating chronic heart failure is not fully understood. It may be that chronic heart failure causes long-term over-activation and stimulation of the sympathetic nervous system, which damages heart function. Lolamine drugs can inhibit the sympathetic nervous system, reduce renin secretion, delay and reverse ventricular remodeling, and improve heart function.

3. Precautions when using Lol drugs 1. Do not abuse: There is no necessary connection between the heart rate and life expectancy of the human body, so taking Lol drugs to slow down the heart rate of healthy people will not increase life expectancy. Only patients with hypertension and coronary heart disease can use Lol drugs under the guidance of a doctor according to the needs of the disease.

2. Large individual differences: The number of β1 receptors in each person's heart is different, so there is a large individual difference in the use of Lol drugs. The treatment dose between different people may differ by several times. Therefore, you should start with a small dose and increase the dose slowly until you "find" the dose that suits you.

3. Take medicine on an empty stomach: Food and drink can affect the absorption of Lol drugs, causing fluctuations in blood drug concentrations, which in turn cause fluctuations in blood pressure. Therefore, Lol drugs should be taken on an empty stomach at least 30 minutes before meals to ensure stable blood drug concentrations.

4. Slowly stop the drug: When using Lol drugs for a long time, sudden stopping of the drug will cause a "rebound phenomenon", causing arrhythmia and worsening of hypertension symptoms. When Lol drugs need to be stopped, they should be adjusted at intervals of 3 days, gradually reducing the dosage until the drug is stopped. The entire withdrawal process should be no less than 2 weeks.

5. Pay attention to contraindications: Lolamine drugs are not suitable for people with severe heart failure and bradycardia. They should abstain from alcohol during medication. People with asthma should use Lolamine drugs, which have less effect on bronchial β2 receptors and are highly selective for β1 receptors, under the guidance of a doctor.

In summary, Lol drugs can both lower blood pressure and protect the heart. They are suitable for young and middle-aged people with elevated blood pressure caused by excessive sympathetic nerve excitement. They are also suitable for patients with coronary heart disease to protect the heart, which can reduce cardiac oxygen consumption and improve cardiac function. During use, it is necessary to pay attention to individual differences and the "rebound phenomenon" when the drug is discontinued. It needs to be used under the guidance of a doctor to be safe and effective. I am pharmacist Huazi, welcome to follow me and share more health knowledge.