Down syndrome trisomy 21 normal value chart

Down syndrome trisomy 21 normal value chart

For pregnant mothers, physical and mental health is a very important indicator, and any small problem in the body may cause serious adverse effects. Therefore, regular checkups should be conducted during pregnancy to prevent the occurrence of symptoms. Among them, Down syndrome screening is one of the prenatal examination methods, which can better understand the baby's health status. Let us learn the basic knowledge of Down syndrome screening below.

Down syndrome trisomy 21 standard value chart

The normal cutoff value for trisomy 21 is 1/250, high risk is greater than or equal to 1 in 250, and low risk is less than 1 in 250. The high risk for trisomy 18 is greater than 1 in 350, and low risk is less than 1 in 350. The OSB standard should be OSB 1:1000.

Is it necessary to do Down syndrome screening?

Although most babies with Down syndrome often miscarry spontaneously in the early stages of their mother's pregnancy, the fertility rate of Down syndrome babies still accounts for 1/600-1/800 newborns, so Down syndrome screening is very necessary. Pregnant women over 35 years old are at high risk for Down syndrome, and it is recommended that pregnant women aged 35 years or older should undergo Down syndrome screening.

Down syndrome is also known as congenital idiocy or trisomy 21. Among the 23 pairs of sex chromosomes in the human body, chromosome 21 is a relatively short pair, with relatively less genetic information on the upper band. Even if abnormalities are found, it will not cause fatal adverse effects. Therefore, babies born with Down syndrome will not necessarily have any abnormalities, repeated vaginal bleeding, or fetal growth retardation. They will usually be born safely and have a long life span.

As everyone knows, because they have one more chromosome than ordinary people, Down syndrome patients have common physical characteristics: flat nose and round eyes. 100% of them have intellectual disabilities and low muscle tone, and men will continue to suffer from infertility. This disease cannot be cured. Patients usually have poor ability to live and work independently, need to attend special schools, and need long-term care from family members, which is a huge burden for a family.

Therefore, regular prenatal check-ups are very necessary for pregnant mothers, which can prevent the occurrence of some diseases and also better understand the growth status of the fetus. In addition, during pregnancy, you should also pay attention to rest, ensure adequate sleep, balanced nutrition, and maintain an optimistic attitude. This will be beneficial to the healthy development of the child and can also relieve the discomfort caused by pregnancy for mothers.

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