Do I need to fast to check estradiol and progesterone?

Estradiol is a hormone secreted by the ovaries. It maintains the secondary characteristics of female friends and promotes endometrial hyperplasia. Its content is related to the development of the uterus and the future conception of girls. Therefore, when we check estradiol, we do not need to fast. Because this hormone is used to check sex hormones, what needs to be distinguished is the time of the test, because the estradiol content in each stage is different.

You do not need to be on an empty stomach to test estradiol and progesterone. You can go to the hospital for the test after breakfast. A blood test is required. It is best to go to the hospital for the test on the third day of your menstrual period. If your menstruation is normal, you do not need to do a sex hormone test if you want to get pregnant. You should pay attention to having sex around the time of ovulation to make it easier to get pregnant. Generally, ovulation occurs about fourteen days before the next menstruation.

1. The relationship between estradiol and progesterone hcg

1. HCG controls the fetal heart rate, estradiol controls the fetal bud, and progesterone prevents the uterus from bleeding and avoids flushing the embryo out. HCG needs to keep rising, estradiol must be guaranteed to be above 700 to have a chance of embryo budding, progesterone must be between 25 and 60 to be safe. If it exceeds 60, you must pay attention to blood coagulation, which will cause fetal arrest. Excessive progesterone can also cause fetal malformations. The higher the progesterone, the better. Estradiol will drop when preparing for embryo budding.

2. Stable progesterone can promote the normal growth of hcg. Estradiol will drop slightly during the growth of the fetal bud, so it is necessary to observe the blood values ​​in time and supplement the drugs in time when they can not meet the needs of the body. This is the so-called optimal period. After six to eight weeks, the fetal heart and fetal bud will never be able to grow steadily.

2. Clinical significance of estradiol

1. Increase: seen in female precocious puberty, male breast development, pregnancy (especially twins or multiple births), estrogen-secreting tumors, ovulation-inducing drugs (such as chlorpheniramine), male feminization, ovarian tumors, anovulatory uterine bleeding and cirrhosis, etc.

2. Decrease: seen in ovarian tumors, hydatidiform mole, intrauterine fetal death, pregnancy-induced hypertension syndrome, hypothalamic tumors, hypopituitarism, ovarian insufficiency, oophorectomy, delayed puberty, primary and secondary amenorrhea, menopause, oral contraceptives, etc.

3. Pathological causes of increased estradiol values: Ovarian diseases: Ovarian granulosa cell tumor, ovarian embryonal tumor, ovarian fat cell tumor, sex hormone-producing tumor, etc., all show ovarian hyperfunction and increased estradiol secretion. Heart disease: myocardial infarction, angina pectoris, coronary artery stenosis.

4. Others: systemic lupus erythematosus, liver cirrhosis, and male obesity.