Mid-term Down syndrome screening high risk

Mid-term Down syndrome screening high risk

Generally, pregnant women will choose to do Down syndrome screening during their prenatal check-up. Down syndrome screening is a test that can exclude fetal malformations with a relatively high accuracy rate. Down syndrome screening generally has early and late tests, usually around 15 to 20 weeks of pregnancy. If the risk is high in the mid-term Down syndrome screening, there is no need to worry too much, because there is a high possibility that there is a problem with the child, but there are also errors and further examination should be carried out.

If the result is low risk, it means the chance of the fetus having Down syndrome is low.

If the result is high risk, it means that the fetus has a higher chance of suffering from Down syndrome, not that the fetus has Down syndrome. Pregnant mothers should not worry too much. Further examination is needed at this time, such as amniocentesis or non-invasive DNA testing.

Amniocentesis is inexpensive and can detect a wide range of items.

The detection accuracy rate is almost 100%. On the one hand, it can detect whether there are abnormalities in the number of chromosomes, and on the other hand, it can also detect whether there are abnormalities in the chromosome fragments. Based on the current level of technology, amniocentesis is still very safe.

If all pregnant women were offered amniocentesis or chorionic villus sampling.

Not only is the cost relatively high, it also increases the chance of miscarriage, so it is not necessary for all women to undergo amniocentesis or chorionic villus sampling. Currently, the best way to prevent Down syndrome is that all young pregnant women undergo Down syndrome screening tests, and those who are shown to be at high risk undergo amniocentesis or chorionic villus sampling. Through amniocentesis or chorionic villus sampling, it can be determined whether the fetal chromosomes are normal and whether the fetus has Down syndrome.

Amniocentesis.

Amniotic fluid is extracted, the cells shed by the fetus in the amniotic fluid are cultured, and the chromosomes of the cells are tested (the fetus's 21 chromosomes are tested). Extracting amniotic fluid: 20 ml of amniotic fluid is collected. The risks are possible infection, amniotic fluid leakage, miscarriage, and the possibility of miscarriage (probability 1/1000). Cultivating the cells shed by the fetus in the amniotic fluid has a success rate of 98/100. Test the chromosomes of cells (test the 21 chromosomes of the fetus), with an accuracy rate of 100/100.

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