Elevated transaminase is a very normal symptom. It does not mean that there is a problem with the liver. It is because transaminase is very sensitive. Many factors can cause transaminase. For healthy people, the results of transaminase tests at different times of the day are different. So don’t think that elevated transaminase means you have a terminal illness. Elevated transaminase will only cause some symptoms in the patient’s body. You should consult a doctor whether it will affect pregnancy preparations. Elevated transaminase is a very common condition and does not necessarily mean that there is a problem with the liver. Because transaminase is very sensitive, many factors can cause the normal value of transaminase to fluctuate. In healthy people, the transaminase measurement results may be different when checked at different times of the day. Transaminase is an essential "catalyst" in the human body's metabolic process and is mainly found in liver cells. When liver cells are damaged by inflammation, necrosis, poisoning, etc., transaminase will be released into the blood, causing an increase in serum transaminase levels. Usually, the main transaminase tested during a physical examination is alanine aminotransferase (ALT). 1% damage to liver cells can double the concentration of ALT in the blood. Therefore, ALT levels can sensitively monitor whether the liver is damaged. symptom Some people do not experience symptoms of high transaminase levels, while others who experience symptoms of high transaminase levels may easily confuse them with symptoms of other diseases. Common symptoms of high transaminase levels include fatigue, poor appetite, insomnia, low-grade fever, aversion to greasy food, nausea, vomiting, abdominal pain, diarrhea, and discomfort in the liver area. Mild symptoms include sweating, drowsiness, thirst, and eye fatigue when reading. In outpatient clinics, the most common symptom of hepatitis B patients is high transaminase. Therefore, hepatitis B patients should be familiar with these symptoms and go to the hospital for diagnosis and treatment in time when these symptoms occur. In general, a mild increase in transaminase levels generally does not cause obvious symptoms, while patients with a larger increase in transaminase levels will experience symptoms such as fatigue, anorexia, nausea, vomiting, and abdominal distension. If the transaminase level rises to more than 500 units in a short period of time, you should consider whether you have acute hepatitis. If you receive timely treatment, acute hepatitis B can be completely cured. standard There are two types of serum transaminases: alanine aminotransferase (ALT) which exists in the cytoplasm of liver cells, and aspartate aminotransferase (AST) which exists in the mitochondria of liver cells. Generally speaking, the normal range for both transaminases is 0-40 IU/L. Elevated ALT activity indicates clinical onset, which often rises rapidly and then falls slowly. Alanine aminotransferase ALT is generally more than ten to dozens of times higher than the normal upper limit. ALT values indicate the degree of inflammatory activity and are not significantly correlated with the management of tissue destruction. Aspartate aminotransferase (AST) reflects the damage to the mitochondria of liver cells and can better explain the degree of damage to liver tissue. When the value of aspartate aminotransferase (AST) is higher than that of alanine aminotransferase (ALT), you should be alert to severe or chronic hepatitis. |
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