Are uterine fibroids serious?

A woman's uterus is very fragile. If it is not carefully protected, various diseases are likely to occur, such as cervical cancer or cervical erosion. Therefore, women must pay more attention to their private hygiene and avoid excessive sexual activity. Some women may develop uterine wall fibroids due to special reasons. So is this disease serious?

Are intramural uterine fibroids serious?

There are many risk factors that contribute to the development or growth of uterine fibroids. Factors that increase the risk of uterine fibroids include: maternal use of estrogen during pregnancy, young age at menarche, nulliparity, late childbearing, obesity, African Americans, and tamoxifen. Factors that reduce the risk of uterine fibroids include exercise, multiple births, menopause, and oral contraceptives.

Modern medicine believes that uterine fibroids are hormone-dependent tumors. Uterine fibroids are common during the childbearing years, are rare before puberty, and shrink or disappear after menopause. Studies have shown that estrogen and progesterone synergistically promote the growth of fibroids. The main mechanism may be that estrogen in the follicular phase upregulates estrogen and progesterone receptors on uterine smooth muscle, and then progesterone promotes the mitotic activity of fibroids in the luteal phase, thereby stimulating the growth of fibroids.

Cytogenetic studies have shown that 25-50% of uterine fibroids have cytogenetic abnormalities, including exchange of chromosome 12 and chromosome 17 fragments, rearrangement of chromosome 12, and partial deletion of chromosome 7.

There are increased expression levels of multiple growth factors and their receptors in uterine fibroids, which are considered to be mediators or effectors of the upregulation of ovarian sex hormones during uterine fibroid formation. However, the possibility of abnormal primary regulation of one or more growth factors cannot be ruled out. Uterine fibroids usually contain excessive extracellular media, which mainly contain fibroblasts and the collagen types I and III they produce. Myoma cells interact with fibroblasts and various growth factors, providing a suitable microenvironment for the formation and growth of myomas.

Treatment of uterine fibroids

1. Use conservative treatment:

Reasonable medication can be used to inhibit the growth of fibroids, but the clinical effect is not very good. It is recommended that you take surgical treatment.

2. Surgical treatment :

Traditional surgical treatment has been gradually eliminated due to its large incisions and severe trauma. The hospital uses the most advanced international surgical techniques, and senior experts perform the surgery. While monitoring with laparoscopy, they use hysteroscopy to perform electroresection of submucosal uterine fibroids. This method has the characteristics of minimal damage, preservation of fertility, and clean removal of fibroids. Many fibroids patients have been successfully restored to health. Expert tips: Some patients take chances and fail to treat fibroids in time and then get pregnant blindly, which can easily lead to early miscarriage. Therefore, women who want to have children should receive timely treatment. Under today's medical conditions, it is entirely possible to preserve the uterus, protect fertility, and remove the fibroids.