In fact, women's physiological cycle is constantly changing. Menstruation does not come on a specific day every month. It is considered that some medications and physical factors may cause menstruation to not come on time. Some people may have menstruation while playing or in special circumstances when riding in a car. This is an emergency and requires emergency treatment. During the period when menstruation is about to come, sanitary napkins should be carried with you. Cycle Changes One of the physiological characteristics of the female reproductive system is its cyclical changes, and menstruation is an important sign of this cyclical change. The menstrual cycle is mainly regulated by the interaction between the hypothalamus, pituitary gland and ovary. The hypothalamus regulates the function of the pituitary gland, and the pituitary gland regulates the function of the ovary. The endometrium undergoes cyclical changes under the action of ovarian hormones. The sex hormones produced by the ovaries, in turn, act on the hypothalamus and pituitary gland, affecting the release of gonadotropin-releasing hormone, follicle-stimulating hormone and luteinizing hormone, which is the so-called feedback effect; when their release is inhibited, it is called negative feedback, and when their release is promoted, it is called positive feedback. The relationship between the changes in blood hormones during a normal menstrual cycle and the ovaries and endometrium is as follows: After the corpus luteum atrophies in the previous menstrual cycle, the secretion of estrogen and progesterone decreases, relieving the inhibition of the hypothalamus and pituitary gland. Gonadotropin-releasing hormone produced by the hypothalamus enters the anterior pituitary through the pituitary portal vein system, promoting the secretion and release of follicle-stimulating hormone and luteinizing hormone. Under the synergistic action of follicle-stimulating hormone and luteinizing hormone, the follicles in the ovaries gradually develop and mature, and produce estrogen, causing proliferative changes in the endometrium. After the follicles mature, the first peak of estrogen appears in the body. The increase in estrogen secretion produces a feedback effect on the hypothalamus and pituitary gland, inhibiting the production of follicle-stimulating hormone, promoting the increase in luteinizing hormone secretion, resulting in a luteinizing hormone peak and triggering ovulation. After ovulation, the corpus luteum is formed and secretes estrogen and progesterone. Under their combined action, the endometrium undergoes typical secretory phase changes. After ovulation, estrogen levels temporarily decrease, followed by a second, lower peak. The large amount of estrogen and progesterone secreted by the corpus luteum inhibits the hypothalamus and pituitary gland through negative feedback, causing the secretion of follicle-stimulating hormone and luteinizing hormone to decrease, and the corpus luteum begins to atrophy. After the corpus luteum atrophies, the secretion of estrogen and progesterone decreases, the endometrium loses the support of sex hormones, necrosis and shedding occur, and menstruation occurs. After the corpus luteum atrophies, the inhibition on the hypothalamus and pituitary gland is also lifted, causing gonadotropin-releasing hormone to be secreted again, and another menstrual cycle begins. |
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