Taking progesterone to expel residual 2 months after medical abortion

Taking progesterone to expel residual 2 months after medical abortion

After medical abortion, the remaining fluid in the uterus must be completely discharged to ensure the complete recovery of the woman's body. Otherwise, it is likely to cause infection problems in women and lead to serious gynecological diseases. It is generally recommended that everyone take some auxiliary medicines, which can help the body discharge lochia as quickly as possible and assist the body in completely recovering health. Therefore, you can consume some flavonoids to help the ovaries achieve health.

1. Progesterone, also known as progesterone hormone and luteinizing hormone, is the main biologically active progesterone secreted by the ovaries. Before ovulation, the amount of progesterone produced per day is 2~3 mg, mainly from the ovaries.

After ovulation, it rises to 20-30 mg per day, most of which is secreted by the corpus luteum in the ovary. Progesterone can protect the female endometrium. During pregnancy, progesterone can provide support and protection for the early growth and development of the fetus, and can also have a certain calming effect on the uterus. In addition, progesterone and estrogen are closely related, and both are very important female hormones. The main function of estrogen is to promote the development and maturation of female secondary sexual characteristics, while progesterone further promotes the development and maturation of secondary sexual characteristics on the basis of the effect of estrogen. There is a synergistic effect between the two.

Obtained by oxidation of pregnenolone. Add dry toluene into a dry reaction pot, add cyclohexanone and pregnenolone, stir to dissolve, evaporate toluene to dehydrate, quickly add aluminum isopropoxide, oxidize at 115°C for 2h, cool to about 80°C, add 5% dilute sulfuric acid with stirring, let stand to separate, remove the water layer, wash the toluene layer with water until it is neutral, then perform steam distillation to remove toluene and cyclohexanone. The mixture was cooled and filtered, and the residue was stirred into a slurry with petroleum ether, filtered, washed with petroleum ether, and dried to obtain crude progesterone. The crude product was dissolved in ethanol, decolorized with activated carbon, and recrystallized to obtain the finished product with a yield of 80%.

1. In the second half of the menstrual cycle, it promotes the growth of endometrial glands, uterine congestion, and endometrial thickening to prepare for the implantation of the fertilized egg. It also reduces the excitability of the uterus during pregnancy, inhibits its activity, relaxes smooth muscles, and allows the embryo to grow safely.

2. Working together with estrogen, it promotes the development of mammary lobules and glands, allowing the breasts to fully develop and prepare for lactation.

3. It closes the cervix, reduces and thickens the mucus, and makes it difficult for sperm to penetrate; in large doses, it has a negative feedback effect on the hypothalamus, inhibiting the secretion of pituitary gonadotropin and producing an ovulation-inhibiting effect.

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