Is fasting progesterone the same as postprandial progesterone?

Female fertility and embryo development are all related to progesterone, because progesterone stimulates the uterus and increases the blood vessels and tissues of the reproductive system. Progesterone is actually a hormone. If the progesterone level is too low, it will cause miscarriage in pregnant women. Excessive progesterone can also prevent female ovulation. Because of different physical constitutions, the progesterone content of each woman is also different. So is fasting progesterone the same as postprandial progesterone?

First, are fasting progesterone and postprandial progesterone the same? Generally speaking, blood hCG and progesterone tests are not affected by diet, and fasting tests are generally not required. Progesterone is a type of progestogen, which is a naturally secreted progestogen in the human body. Progesterone has a negative feedback regulatory effect. It can inhibit its own secretion and also inhibit the secretion of estrogen. The main function is to determine whether the ovaries have ovulated and to understand the function of the corpus luteum. If a pregnant woman has low progesterone, miscarriage is very likely to occur. For unmarried women, low progesterone may lead to infertility in the future. If you are currently pregnant, you need to assess whether your progesterone level is low based on your gestational age. It is recommended to strengthen nutrition and keep bowel movements smooth.

Second, the main function of progesterone in non-pregnant adult women is to cooperate with estrogen to participate in the functional activities of maintaining the normal menstrual cycle; during pregnancy, progesterone is mainly produced by the placenta, and its content increases with the gestational age. Progesterone, on the basis of the action of estrogen, keeps the fertilized egg implanted in the uterus and maintains the smooth progress of pregnancy.

Third, immune protection. Progesterone has immune protection and can suppress immune responses. A study implanted certain tumor cells into the uterus of animals. Only in animals injected with progesterone were the cells not rejected and implanted into the uterine wall, indicating that progesterone can suppress the immune response. This also shows that when a woman is in a normal pregnancy, the increase in progesterone can prevent the embryo from being rejected by the mother and maintain the pregnancy. When there is a lack of progesterone, the embryo may be rejected by the mother and cause miscarriage.

Are fasting progesterone and postprandial progesterone the same? The above content introduces the role of progesterone: blastocyst implantation. During ovulation, under the action of progesterone secreted by the corpus luteum, the endometrium transforms from the proliferative phase to the secretory phase, making the endometrium receptive to embryo implantation. Decidual cells are transformed from endometrial stromal cells and contain glycogen granules, which provide nutrition to the blastocyst. Progesterone can induce the decidualization of endometrial stroma and regulate the expression of various implantation-related factors in an autocrine or paracrine manner.