What are the side effects of Letrozole?

In modern life, women’s physical health is getting worse and worse, which has affected the reproductive system, causing low fertility or loss of fertility, causing great harm to women’s family life. Women's reproductive problems are mainly ovulation problems. Taking drugs to deal with ovulation disorders is very effective. For example, letrozole is a commonly used ovulation-inducing drug. However, what are the side effects of letrozole inducing ovulation?

1. The principle of letrozole inducing ovulation

The function of letrozole is to block the conversion of androgens into estrogen at the level within the ovaries, allowing androgens to accumulate in the follicles, which can promote the development of follicles and also improve the ovaries' ability to respond to hormones. It can eliminate the negative feedback from the hypothalamus to the pituitary gland, promote the secretion of follicle stimulating hormone (FSH), and achieve the purpose of promoting ovulation.

If normal patients take it orally, there are basically no side effects. However, for elderly infertile patients, long-term use of this medicine will cause mild or moderate liver cirrhosis, and there will also be some adverse reactions, such as fever, headache, chest tightness, etc. Once this happens, infertile patients should stop taking the medicine immediately, whether there are allergic reactions, etc., and premenopausal women should not use this medicine easily, because it will cause endocrine disorders in women with normal menstruation and cause harm to women's bodies.

Generally, the initial dose is 2.5 mg. Take it again on the fifth day of the menstrual period. After more than ten days, go to the hospital to check the ovulation status. If there is no obvious effect, you can increase the dose. Data show that generally, reasonable dosage can be controlled within the range of 2.5-7.5 mg to ensure the effectiveness of the medication.