What to do if the follicle does not rupture

Unruptured follicles are a condition in which the follicles are abnormal. After this happens, it can be caused by many reasons, including immature follicles, or some other reasons may lead to unruptured follicles. Once unruptured follicles occur, we should take some measures to treat them, such as surgical treatment, etc. So what should we do if the follicles do not rupture?

Expectant treatment: LUFS occurs accidentally in some patients. For patients with no history of infertility or who discover LUFS for the first time, the lutein cyst sometimes disappears naturally before the next menstruation and does not need to be treated for the time being.

Drug-induced follicle rupture: Individualized ovulation induction plan is formulated and optimized, and after the follicles mature, high-dose HCG or short-acting GnRH-a is injected alone or in combination.

Mechanical treatment: 48 hours after the drug-induced follicle rupture, if the follicle still exists, the follicle can be gently and moderately squeezed by hand under ultrasound guidance. If the follicle still does not rupture, follicle puncture surgery can be performed through the posterior fornix of the vagina under ultrasound guidance to help the egg rupture and be discharged, while also guiding sexual intercourse to try for pregnancy. However, the moderate compression method has limited effect, the puncture method is not cost-effective, and there may be risks such as potential damage and infection, so it is not widely used in clinical practice.

IVF: Patients who still fail to conceive after using the above methods or who have recurrent LUFS are recommended to consider IVF treatment. Through egg retrieval surgery, the eggs are removed and fertilized with sperm in vitro to solve the fertility problem.

Psychological treatment: Relaxation and psychological counseling when necessary can help restore normal ovulation.