What does high estradiol after transplantation mean?

After embryo transfer, if estradiol is too high, it is not conducive to the implantation of the fertilized egg. At this time, the estrogen level should drop, while the progesterone level has not risen, which is conducive to implantation. If the hormone level is too high, it will affect the embryo transfer and the survival of the fertilized egg. Therefore, you should go to the hospital for examination in time to see if the transplant is successful.

1. What is estradiol?

Estradiol is an estrogen therapy that is absorbed through the skin. Estrogen can stimulate cells to synthesize DNA, RNA and various proteins in corresponding tissues. The main effects of estradiol are to regulate female characteristics, the maturation of accessory sexual organs, and control the menstrual and ovulatory cycles.

2. The role of estradiol

Estradiol can promote endometrial proliferation and enhance the contraction of uterine smooth muscle.

It promotes the development and proliferation of mammary ducts, but larger doses can inhibit the release of prolactin from the anterior pituitary, thereby reducing milk secretion.

Anti-androgenic effect.

Lowers blood cholesterol and increases calcium deposition in bones.

3. What is the normal value of estradiol?

The normal value of estradiol will change differently at different times, and it will also be different for each specific person, but in general, the estradiol level in adults fluctuates between 48 and 1835 pmol/L.

The estradiol level of females before puberty is: 0～121pmol/L

The value in the follicular phase is: 37-330 pmol/L

Ovulation period value: 367～1835pmol/L

Luteal phase values ​​are: 184-881pmol/L

The value for males before puberty is: 0-148 pmol/L

Adult value: 0～942pmol/L

Causes of elevated estradiol

Estradiol is secreted by female ovaries, so if the estradiol value is unstable, it is likely due to problems with the ovaries.

If a woman has high estradiol levels, it may be caused by certain other diseases in the body, such as myocardial infarction, angina pectoris, coronary artery stenosis, systemic lupus erythematosus, cirrhosis, etc.