What are multifunctional ovaries?

What are multifunctional ovaries?

Multifunctional ovary is also known as polycystic ovary syndrome, which is a common disease manifestation in women of childbearing age. It is mostly caused by endocrine or metabolic abnormalities. Female patients are prone to anovulation, which can easily lead to hyperandrogenemia, irregular menstruation, dysmenorrhea, hirsutism or infertility, and often cause some female endocrine diseases.

At present, there are two kinds of research on the etiology of PCOS: non-genetic theory and genetic theory.

1. Non-genetic theory of PCOS

Studies have shown that the hormonal environment in the uterus during pregnancy affects the endocrine state of the individual in adulthood. Exposure to high-concentration androgen environments during pregnancy, such as mothers with a history of PCOS or mothers with congenital adrenal hyperplasia and poorly controlled hyperandrogenism, can easily lead to ovulatory dysfunction after puberty.

2. PCOS Genetics Theory

The main basis of this theory is that PCOS tends to run in families. Familial ovulatory dysfunction and polycystic ovarian changes suggest that the disease has a genetic basis. Hyperandrogenism and/or hyperinsulinemia may be genetic characteristics that PCOS family members also suffer from. The effect of insulin on promoting ovarian androgen production is also affected by genetic factors or genetic susceptibility.

Family members with oligoovulation, hyperandrogenism, and polycystic ovaries have an increased prevalence of hyperinsulinemia in women and premature hair loss in men. Cytogenetic studies have shown that PCOS may be inherited in an X-linked recessive, autosomal dominant or polygenic manner.

Through whole genome scanning, the largest number of genetic genes related to PCOS were discovered, such as candidate genes for steroid hormone synthesis and related functions, androgen synthesis-related regulatory genes, insulin synthesis-related genes, carbohydrate metabolism and energy balance candidate genes, gonadotropin function and regulation candidate genes, adipose tissue-related genes, and chronic inflammation-related genes.

In short, the etiology research of PCOS cannot confirm that the disease is caused by a certain gene site or a certain gene mutation. Its onset may be related to the action of some genes under the influence of specific environmental factors, leading to the occurrence of the disease.

<<:  What are the symptoms of immature uterus

>>:  What to do if your uterus prolapses after giving birth

Recommend

What to do if you have breast allergies during lactation

Allergies are very common in life and usually for...

What is the clinical significance of routine cervical examination?

For everyone in modern society, it is important t...

Consequences of chronic pelvic inflammatory disease

Although pelvic inflammatory disease is a relativ...

How long is it normal to have a flat tire?

Miscarriage is also known as threatened abortion....

How to remove deep wrinkles under eyes

Wrinkles can be said to be women’s natural enemy....

Clinical manifestations of cephalopelvic disproportion

It is said that natural childbirth is good for bo...

How long does it take for breasts to grow during pregnancy?

When does breast growth start during pregnancy? T...

Nucleic acid, antigen, antibody, what are they?

Author: Guo Pengfei, Shanghai Tenth People's ...

No bleeding for a few days after abortion

When women have an unexpected pregnancy, they wil...

What are the benefits of putting a ring

There are indeed many advantages to using contrac...

How long does it usually take for menstruation to come after an abortion?

Everyone knows that menstruation will not come du...

What to do if the IUD is displaced

Wearing an IUD is a very common contraceptive met...