What is the effect of high transaminase on the fetus?

In order to diagnose substantial damage to liver cells, it is often necessary to measure the level of transaminase. The normal value of transaminase is generally between 0 and 40 units. If it exceeds this range, the transaminase is considered to be high. After it is high, first of all, the pregnant woman's liver has been seriously damaged. Secondly, after the transaminase metabolism is abnormal, the liver's detoxification function is seriously affected, and toxic substances cannot be metabolized in time. Liver disease is further aggravated, thus affecting the health of the fetus.

After pregnancy, the burden on the liver increases. Liver diseases before pregnancy, such as acute and chronic hepatitis, cirrhosis, etc., have adverse effects on pregnant women and fetuses. Therefore, liver function tests, including transaminase, bilirubin, albumin, etc., must be performed during prenatal examinations. During pregnancy, a small number of pregnant women will have elevated transaminase levels, which is common in pregnant women with severe early pregnancy reactions (but some pregnant women do not have any early pregnancy reactions and their transaminase levels will also be elevated). Generally, only the transaminase level is elevated, and other parameters are within the normal range. In this case, the doctor will ask the pregnant woman whether she has nausea, vomiting, upper abdominal discomfort, etc., and will also perform liver palpation and percussion. At the same time, he will understand the results of routine tests during pregnancy, namely the hepatitis A, hepatitis B, and hepatitis C antibody tests. If the pregnant woman does not feel uncomfortable, the liver is not large, and there is no percussion pain, and the hepatitis A, hepatitis B, and hepatitis C antibodies are all (-), then the doctor will prescribe some liver-protecting drugs for treatment or no medication.

When the liver function is re-examined, the transaminase levels of many pregnant women are normal. However, if the transaminase level continues to not decrease, or instead increases, or other liver function tests show abnormalities, further examinations should be conducted, including viral hepatitis markers, such as hepatitis A, B, C, D, E, and G antibodies or virus tests, liver and gallbladder B-ultrasound, etc., to understand the cause of the abnormal transaminase level. If necessary, other tests should be performed, such as blood ammonia and bile, coagulation function tests, etc.

Pregnant women should know that hepatitis B is not a hereditary disease, so if their transaminase levels are high, the hepatitis B virus will be transmitted to the fetus. Hepatitis B virus can be transmitted through the blood, so when giving birth, you must find a large hospital and tell the doctor in advance that you have hepatitis B. This way, you can avoid the child being infected with the hepatitis B virus during delivery as much as possible.