What causes hydatidiform mole?

Hydatidiform mole can be roughly divided into complete hydatidiform mole and partial hydatidiform mole. The cause of this disease is very complicated. Some people believe that it is caused by nutritional reasons, some believe that it is caused by infection, and some believe that hydatidiform mole is caused by endocrine disorders. Current medical research has found that racial factors and mental reasons are related to hydatidiform mole. The causes of hydatidiform mole are introduced below.

Modern medical research still does not clearly reveal the true cause of hydatidiform mole. However, controlled case studies have found that the occurrence of hydatidiform mole is related to nutritional status, socioeconomic status and age. Age is a significant related factor in etiology. The incidence of hydatidiform mole in women over 40 years old is 10 times higher than that in young women. Women under 60 years old are also at high risk of complete hydatidiform mole. Women in these two age groups are prone to fertilization defects. Partial hydatidiform mole has nothing to do with the age of the pregnant woman.

Causes of partial hydatidiform mole. Generally, only part of the placental villi undergo vesicular degeneration, and there are still living or dead embryos in the uterine cavity, which is often accompanied by developmental delay or multiple malformations. Microscopically, the villi are of varying sizes, often fan-shaped, with irregular contours, obvious invagination of the trophoblastic matrix, partial interstitial edema, and mild trophoblastic proliferation. Fetal blood vessels and the nucleated red blood cells therein can be seen in the interstitium.

Causes of complete hydatidiform mole. Gross examination shows that the vesicles are shaped like bunches of grapes, ranging in size from a few millimeters to several centimeters in diameter, connected by fine cellulose, often mixed with blood clots and decidual fragments. The vesicular mass fills the entire uterine cavity, and the fetus, its appendages, or any traces of the fetus cannot usually be found during examination. Microscopically, the villi vary in size, are often fan-shaped, have regular contours, are characterized by trophoblastic proliferation, interstitial edema, and disappearance of intrastitial fetal blood vessels.

Through the above introduction, everyone must have known that the cause of hydatidiform mole is not very clear at present. It is precisely for this reason that it is more difficult to prevent hydatidiform mole. At present, the main focus for hydatidiform mole is early detection and early treatment. You can go to the hospital for a B-ultrasound examination to confirm hydatidiform mole. Once discovered, in addition to regular follow-up, you should continue treatment.