How to know if it is a hydatidiform mole

In some women, the chorionic matrix microvessels may disappear, and after disappearance, chorionic matrix fluid will form, and then many small vesicles of varying sizes will be produced. These small vesicles are the so-called hydatidiform mole. Molar pregnancy can involve the placental villi and eventually even fill the entire uterine cavity with molar pregnancy. After the occurrence of hydatidiform mole, the fetus will most likely die, so this disease must be actively examined and treated. The following describes the inspection method.

Diagnosis based on medical history: irregular vaginal bleeding after menopause, uterus larger than the month of menopause and softened, and no fetal movement or heart rate when the uterus is 5 months pregnant. If the fetal body cannot be palpated, preeclampsia and eclampsia appear early, bilateral ovarian cysts and signs of hyperthyroidism should be suspected to be a hydatidiform mole. If grape-like vesicular tissue is seen in the vaginal discharge, the diagnosis is basically established.

The accurate quantitative test of hCG is an important test for the diagnosis and follow-up of hydatidiform mole. The amount of hCG is small at the beginning of a normal pregnancy, reaches a peak at 8 to 10 weeks of pregnancy, and then gradually decreases. After the gestational age (100 days), hCG decreases significantly. In twin (or multiple) pregnancies, the hCG level is also higher than that in single pregnancies. In hydatidiform mole, the hCG level is much higher than normal and remains at a high level. In addition to checking whether the serum hCG level of normal non-pregnant women is normal and whether their menstruation is normal, we should also pay attention to whether the above symptoms are present.

Flow cytometric examination of hydatidiform mole: the chromosome karyotype of complete hydatidiform mole is diploid, while that of partial hydatidiform mole is triploid.

Ultrasound examination: In a normal pregnancy, the gestational sac can be seen at 4-5 weeks of pregnancy, the heart tube pulsation can be seen at 6-7 weeks of pregnancy, the fetal heartbeat can be detected as early as 6 weeks of pregnancy, and can be heard after 12 weeks of pregnancy. In hydatidiform mole, the uterine cavity appears as coarse dots or falling snow. No gestational sac is visible, and there are no fetal structures or fetal heartbeat signs. Only uterine blood flow murmurs can be heard, but no fetal heartbeat.

When a woman has a hydatidiform mole, in addition to scientific examinations, there are some symptoms of hydatidiform mole that can be used as a basis for diagnosis. For example, if a woman has vaginal bleeding, frequent abdominal pain, finds that her uterus is obviously enlarged, or suddenly has amenorrhea, she may have a hydatidiform mole and should go to the hospital for a detailed examination.