What should pregnant women pay attention to when prolactin is high

Prolactin is a hormone secreted during pregnancy. The amount of secretion will vary depending on the environment. High prolactin levels will have a certain impact on pregnant women. It can also lead to upper respiratory tract infections, etc. Let’s take a look at what pregnant women with high prolactin levels should pay attention to? I hope the following information can help you.

The secretion of prolactin is pulsatile and varies greatly throughout the day. The pulse amplitude of endocrine secretion increases rapidly within 1 hour of sleep, then the secretion level remains at a high level during sleep and begins to decline after waking up. The serum secretion concentration of lactase at 3 or 4 o'clock in the morning is twice that at noon.

The secretion of prolactin is affected by many factors. In addition, drugs such as progesterone, diazepam, cortisol, strenuous physical activity, trauma and other acute stress situations can cause increased secretion of lactone. Some drugs can also cause an increase in secretocrine lactase.

Long-term use of drugs such as reserpine, chlorpromazine, and morphine can inhibit the release of prolactin inhibitory factor by changing the production, absorption, and metabolism of dopamine, resulting in excessive secretion of prolactin, leading to amenorrhea and lactation. Oral contraceptives can cause the pituitary gland to secrete increased lactogenic hormone and decreased gonadotropin, which can lead to amenorrhea and milk overflow. Some people who take oral contraceptives cannot get pregnant immediately for this reason.

There are other reasons that can also lead to increased secretion of lactogen. Diseases such as primary hypothyroidism, idiopathic amenorrhea and galactorrhea syndrome, primary hyperthyroidism, renal insufficiency, bronchial cancer, etc. can also cause elevated secretolactone.

One of the main causes of hyperprolactinemia is pituitary tumors. This is because the tumor is composed of cells that secrete prolactin. These cells are out of control and secrete prolactin without restraint. At the same time, the increase in prolactin may also be caused by pressure on the pituitary stalk. If the level of secretolactone in the blood is too high, it is called hypersecretinemia. These people often have symptoms such as breast swelling and pain, milk overflow, infrequent menstruation or even amenorrhea. Therefore, it is sometimes called the amenorrhea-galactorrhea syndrome. Among patients with hypersecretinoinemia, about 1/4 are caused by pituitary tumors, and some may be caused by hypothalamic and pituitary dysfunction, hypothyroidism, renal insufficiency, malignant tumors in other parts of the body, chest wall injury and drug effects.

Elevated prolactin can significantly inhibit the normal secretion of pituitary stimulating hormones (such as follicle-stimulating hormone and luteinizing hormone), affecting the normal development of ovarian follicles, ovulation function and pregnancy function. The reduced secretion of follicle-stimulating hormone will directly lead to the development disorder of the ovarian follicles in the ovary, which will be weak or incomplete (B-ultrasound observation can show ovarian follicles with a diameter of less than 18 mm or smaller), and ultimately cannot conceive; while the insufficient secretion of progesterone (luteinizing hormone) will cause the corpus luteum to be dysfunctional, making it difficult to maintain the fertilized ovarian follicles to continue implantation and development (such as the basal body temperature test shows a low temperature phase below 36.8℃), making it difficult to get pregnant, and even if pregnancy is achieved, miscarriage is very likely to occur.

In addition to physiological reasons, there are also pathological reasons for high prolactin levels in pregnant women. Pregnant women are a relatively special group. When treating diseases, they should not blindly choose medicines for the disease. They should choose carefully and pay attention to dosage, etc. Some medicines should not be used by pregnant women. So be careful.