Causes of endometrial thickness 1.1

The female body structure is very complex. Once gynecological diseases occur in the body, it will cause great harm to the female body and may even lead to infertility. Endometrial thickening is a common gynecological disease of the nose tip. However, due to many reasons, women can have thick endometrium. Among them, endometrial thickness of 1.1 is a relatively common phenomenon. If we want to get better treatment and prevention, we must grasp the reasons. Let’s understand the causes of endometrial thickness of 1.1.

The endometrium is the layer that makes up the lining of the mammalian uterus. The endometrium responds to both estrogen and progesterone and therefore changes dramatically during the sexual cycle (estrus, menstrual cycle). Estrogen can cause uterine hypertrophy, and progesterone can promote special changes in the endometrium in the early stages of pregnancy, or change the properties of the endometrium so that it has the ability to produce decidua. The endometrium is covered with mucosa, which is composed of the mucosal epithelium and the underlying lamina propria. The mucosal epithelium is columnar epithelium, cuboidal epithelium or stratified columnar epithelium. When estrogen is secreted, each epithelial cell will grow and divide to increase in number. The part of the lamina propria below the mucosal epithelium is called the functional layer, into which epithelial cells enter to form uterine glands and respond to estrogen. The lower layer of the functional layer is called the basal layer, which is rich in blood vessels.

Causes of endometrial thickness 1.1

The causes of endometrial hyperplasia are not yet fully understood, but the following phenomena and facts indicate that long-term estrogen stimulation is the main cause of the disease.

Anovulation may occur in adolescent girls, perimenopausal women, or in cases of disorder in a certain link of the hypothalamus-pituitary-ovarian axis, polycystic ovary syndrome, etc. The endometrium is continuously affected by estrogen for a longer period of time without the opposition of progesterone and lacks the transformation of the cyclical secretory phase, and is in a state of hyperplasia.

In postmenopausal women receiving estrogen replacement therapy (ERT), endometrial hyperplasia was observed in 20% of women taking estrogen alone for 1 year.

Endometrial hyperplasia has also been observed in postmenopausal women with advanced breast cancer who have received long-term tamoxifen (TAM). Tamoxifen has a weak estrogen-like effect.

For women, gynecological diseases may occur differently in different age groups and with different physiques. The above is an introduction to the cause of endometrial thickness of 1.1. After understanding it, Rong Guo should also make judgments based on his own physical condition when encountering such symptoms. In addition, women should also pay attention to their personal hygiene and maintain a happy mood.