What is endometrial receptivity

I believe many friends are unfamiliar with endometrial receptivity and don’t know what endometrial receptivity means. So what is endometrial receptivity? Next. This article will introduce you to the relevant content about endometrial receptivity. If you want to know what endometrial receptivity is, you may wish to continue reading! Please see the detailed introduction below.

Endometrial receptivity refers to a state of the endometrium in which the blastocyst can adhere, penetrate the endometrium and induce a series of changes in the endometrial stroma, and finally implant into the endometrium. This period of time is called the "implantation window", which is generally 6 to 10 days after ovulation, that is, the 20th to 24th day of the normal menstrual cycle.

There are many factors that affect endometrial receptivity, including endometrial thickness, morphology, etc. The thickness, morphology and blood flow distribution of the endometrium can be displayed by ultrasound images. There is a special junction area between the myometrium and the endometrium, which appears as a low-echo thin layer under ultrasound. This area plays an important role in endometrial receptivity.

In natural pregnancy or assisted reproductive technology, the quality of the embryo and the receptivity of the endometrium are the key factors for successful pregnancy. The most commonly used and simplest method to evaluate endometrial receptivity is to measure the thickness of the endometrium using B-ultrasound. Some studies believe that endometrial thickness is an important factor in predicting pregnancy outcomes. Appropriate thickness of the endometrium is a prerequisite for embryo implantation. However, it is a clinical consensus that an endometrium that is too thin can lead to a significant decrease in the embryo implantation rate. However, its mechanism is still not fully understood, resulting in the lack of effective treatment.

The thickness of the endometrium during the menstrual cycle can reflect the functional status of the endometrium. The endometrium with moderate thickness is easy for the embryo to implant. Some scholars have studied that the optimal range of endometrium suitable for implantation is ≥10 mm. When the endometrial thickness is <5 mm, no pregnancy occurs. Therefore, the thickness of the endometrium is related to ER. However, some scholars hold the opposite view, believing that there is no correlation between endometrial thickness and pregnancy rate. Therefore, the relationship between endometrial thickness and pregnancy rate is still controversial. However, it is currently generally recognized in ART treatment that endometrial thickness <8 mm has a strong negative predictive value.

Studies have shown that when the endometrial thickness is >8mm, the endometrial receptivity is >78%; when the endometrial thickness is <8mm, the endometrial receptivity is <17%. The menstrual cycle is 21 days and the thickness of the endometrium can reach 15-16mm. Although there is a clear relationship between endometrial thickness and pregnancy rate, an endometrial thickness of 6-7mm can also achieve a higher pregnancy rate when the blastocyst quality is good. Some studies have shown that 88.2% of successful pregnancies have an endometrial thickness of 9-12 mm and an ultrasound type of A. However, subsequent studies have confirmed that endometrial thickness has nothing to do with pregnancy outcomes.

The above is an introduction to what endometrial receptivity is. I believe that after reading the above introduction, you already know what endometrial receptivity is. This knowledge can help us better understand the indicator of endometrial receptivity. I hope that through the introduction of this article, it will be helpful to friends who want to understand what endometrial receptivity is.