What is the disease of vaginal granulation?

If granulation tissue grows at the vaginal opening, you must first find out the specific cause of the disease and determine what kind of disease it is before taking appropriate treatment. Usually, when this symptom appears, it may be due to a tumor or genital warts. After the diagnosis is confirmed, targeted treatment can be given so that your symptoms will not become so serious. This situation mostly occurs among young female friends.

1. Typical genital warts

The genitals and perianal area are the most common sites. In men, it is more common in the foreskin, frenulum, coronal sulcus, glans penis, urethral orifice, penis shaft, perianal area, rectum and scrotum. In women, it is more common in the labia majora and minora, posterior symphysis, vestibule, clitoris, cervix and perianal area. It can occasionally be seen in areas other than the genitals and perianal area, such as the armpits, umbilicus, mouth, breasts, and between the toes. Female vaginitis and male foreskin are factors that promote the occurrence of genital warts.

The lesions initially appear as small, light red papules, which gradually increase in size and number, and are distributed singly or in clusters. They are moist and soft, with an uneven surface and appear as nipple-like, cockscomb-like, or cauliflower-like protrusions. Red or dirty grey. The roots often have pedicles and are prone to erosion and exudation, and bleed easily when touched. Purulent secretions often accumulate between the cracks of the skin lesions, causing a foul odor, and secondary infection may occur due to scratching. This disease often has no subjective symptoms, and some patients may experience foreign body sensation, pain, itching or pain during sexual intercourse. Genital warts in the rectum may cause pain, blood in the stool, and a feeling of tenesmus.

2. HPV subclinical infection

HPV infection is clinically not recognizable to the naked eye, but evidence of HPV infection can be found by acetic acid whitening test (local whitening after smearing or wet compressing with 5% acetic acid solution), tissue pathology or nucleic acid detection technology.

3. Relationship with tumors

A large amount of epidemiological data shows that HPV infection (mainly high-risk HPV, such as HPV-16 and HPV-18) is closely related to the occurrence of genital cancers, such as cervical cancer and penile cancer.

The prognosis is generally good after treatment. However, no matter which treatment method is used, recurrence is possible.

Topical application or wet compress of 3% to 5% acetic acid solution for 5 to 10 minutes can cause whitening in the HPV-infected area, the so-called "acetic acid whitening phenomenon." However, the specificity is not high, and some chronic inflammations, such as candidal vulvitis, genital trauma and nonspecific inflammation, may result in false positives.