Urine routine leukocyte esterase +2

Leukocyte lipase is a specific enzyme contained in human leukocytes. This enzyme is often used in clinical medicine to detect the presence of leukocytes in sample collection. However, leukocyte lipase is only present in monocytes and not in other body cells. So, what does a urine routine test of leukocyte lipase + 2 mean? Let's have a simple understanding of this issue. I hope the following points will be helpful to everyone!

What does urine routine test white blood cell lipase +2 mean?

Urinalysis examination shows leukocyte lipase + 2. This condition is considered to be a urinary tract infection and other symptoms. If accompanied by abnormal symptoms such as frequent urination, urgency, inability to hold urine, and painful urination, antibiotics can be used for treatment. If the disease is not cured after long-term treatment, urine culture plus drug sensitivity test can be done. According to the results of the drug sensitivity test, a certain amount of reasonable antibiotics can be used, which generally has a better effect. You can also use traditional Chinese medicine for conditioning. Traditional Chinese medicines such as Bazheng Powder (Dianthus superbus, Juncus effusus, Poria cocos) and Sanjin Tablets can clear away heat and dampness, accelerate urine metabolism, and treat infections. At the same time, you can drink more water and regularly maintain routine urine tests.

Leukocyte esterase (LE) is a specific enzyme contained in human leukocytes. When inflammation occurs in the body, the chemotaxis of polynuclear leukocytes gathers in the inflammatory path and releases a large number of LE. LE hydrolyzes 5-bromo-4-chloro-3-indoleacetate to release bromoindole. The latter causes color change under the condition of aerobic exercise, and the color depth is proportional to the specificity of LE.

However, this type of enzyme only exists in monocytes, not in other cells. Therefore, it is not possible to test other types of white blood cells, but only monocytes, which are commonly known as inflammatory cells. This positive result indicates the presence of white blood cells, that is, monocytes, in the sample tested, indicating the presence of inflammation, but it cannot indicate what the cause of the infection is.

What does high white blood cell count in urine test indicate?

The leukocyte count in urine routine examination is a very important item in urine routine examination. There are two items related to the leukocyte count: one is the dry chemical leukocyte lipase, and the second is the total number of leukocytes in it, or the total number of leukocytes observed under a microscope. If the leukocyte lipase is positive and a large number of white blood cells are seen under the microscope, it is generally seen in inflammation of the genitourinary system and adjacent organs. Urogenital tract inflammation is a common disease in clinical medicine. When inflamed, an increase in the number of white blood cells can be seen under a microscope in the urine, which may be accompanied by an increase in the number of blood cells. Secondly, the patient has corresponding clinical manifestations, and the clinician can diagnose inflammation of the genitourinary system. If the leukocyte lipase is positive, but the total number of white blood cells or the total number of white blood cells under the microscope is normal, it is usually caused by contamination in the urine sample collection. In particular, the urine sample collection of female patients is easily contaminated by female secretions, resulting in positive leukocyte lipase, so there is no need to worry.