What is the role of estradiol in pregnancy?

After a woman becomes pregnant, the secretion of hormones in her body changes greatly. She will secrete more hormones that are beneficial to pregnancy. For example, estradiol is a very important hormone, which has many functions for pregnant women. For example, it can promote the transformation of the endometrium, make the uterus more suitable for fetal survival, and help secrete milk, etc. The following is a detailed introduction to the role of estradiol in pregnancy.

1. Estradiol in early pregnancy

Estradiol is secreted by the ovarian follicles and can also be produced in large quantities by the placenta in women three months after pregnancy. Its main function is to promote the transition of the endometrium to the proliferative phase and promote the development of female secondary sexual characteristics. It can cause endometrial hyperplasia, strengthen the contraction of uterine smooth muscle, cause breast hyperplasia, and antagonize androgens. During normal pregnancy, the estradiol level in the blood increases with the pregnancy cycle, and the increase is more obvious in twin and multiple pregnancies.

2. Estradiol reference value

The normal reference value for estradiol is: 12.3-30.7pg/ml. The test kits in each hospital are different, so the reference values ​​for the six hormone items are also different. In this case, it is recommended that you refer to the reference values ​​on your test report to see if there are any abnormalities. If there are any abnormalities, targeted treatment is needed as soon as possible. The clinical significance of hormone levels checked at different stages of menstruation is different. There is no unified and fixed testing equipment in each hospital, and the testing reagents are different.

2. Embryo

During pregnancy, as long as estradiol is maintained above 1000pmol, there will generally be a fetal heartbeat. After the baby's fetal heartbeat appears, don't think that estradiol is useless. It is still very important at this time. Many people find that the fetus stops growing soon after estradiol decreases. During this period, there are no symptoms of bleeding or abdominal pain, so they feel that there is no need to preserve the fetus. This is the most terrifying thing.

Clinically, there is no strict regulation on the normal range of estradiol in a few weeks of pregnancy, but no matter what, the hormone must maintain a steady upward trend in the early stages of pregnancy, so pregnant women are usually required to monitor it several times in a row. When pregnancy is just confirmed, it is best to control the estradiol level above 300pmol. If it rises slowly afterwards, estrogen should be supplemented in time. Generally, if it can reach 700-800pmol, the baby basically has an embryo. Sisters whose early embryo grows slowly can check their endocrine system to find out if this is the reason.