Gynecological inflammation is a disease that troubles many female friends, because even after treatment, the disease will recur again and again, making patients feel that their bodies are getting worse and worse. Therefore, it is necessary to take medication in the early stages to control the onset of the disease. In fact, the most common drugs are antibiotics, which work quickly and the effect is very significant. The main treatment is antibiotics, and surgery if necessary. Antibiotic treatment can eliminate pathogens, improve symptoms and signs, and reduce sequelae. With active treatment with appropriate antibiotics, most pelvic inflammatory disease can be completely cured. Principles of antibiotic treatment: empirical, broad-spectrum, timely and individualized. It is reasonable to select antibiotics based on susceptibility testing, but antibiotic treatment usually needs to be given before laboratory results are obtained. Therefore, initial treatment is often based on experience. Since the pathogens of pelvic inflammatory disease are mostly Neisseria gonorrhoeae, Chlamydia, and mixed infections of aerobic and anaerobic bacteria, and aerobic and anaerobic bacteria are divided into Gram-negative and Gram-positive, the choice of antibiotics should cover the above pathogens, and broad-spectrum antibiotics and combination drugs should be selected. Timely medication within 48 hours of diagnosis of pelvic inflammatory disease will significantly reduce the occurrence of sequelae. The specific plan selected is based on comprehensive considerations such as hospital conditions, patient acceptance, drug effectiveness and cost-effectiveness. Commonly used regimens: ① Ceftriaxone sodium 250 mg, single intramuscular injection, or cefoxitin sodium 2 g, single intramuscular injection, and oral administration of probenecid 1 g at the same time, and then change to doxycycline 100 mg, twice a day, for 14 consecutive days, and oral administration of metronidazole 400 mg, twice a day, for 14 consecutive days; or other third-generation cephalosporins can be used in combination with doxycycline and metronidazole. ② Ofloxacin 400 mg, orally, twice a day, or levofloxacin 500 mg, once a day, and take metronidazole 400 mg, 2-3 times a day, for 14 days; or moxifloxacin 400 mg, once a day, for 14 days. 1) Ineffective drug treatment : If the body temperature of a fallopian tube, ovarian abscess or pelvic abscess does not drop after 48 to 72 hours of drug treatment, or the patient's poisoning symptoms worsen or the mass increases, surgery should be performed promptly to avoid abscess rupture. 2) Abscess persists : The condition improves after drug treatment and the inflammation is controlled for several days (2 to 3 weeks). If the mass still does not disappear but has become localized, it should be surgically removed to avoid another acute attack in the future. 3) Abscess rupture : Sudden worsening of abdominal pain, chills, high fever, nausea, vomiting, abdominal distension, and resistance to pressure on the abdomen or signs of toxic shock should be suspected. If the abscess ruptures and is not diagnosed and treated in time, the mortality rate is high. Therefore, if abscess rupture is suspected, laparotomy should be performed immediately while also initiating antibiotic treatment. |
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