Will there be a hydatidiform mole in test tube pregnancy?

With the development of medical technology, many infertile families have welcomed new life through in vitro fertilization. Most people who undergo in vitro fertilization have different fallopian tubes or problems with sperm quality. In simple terms, in vitro fertilization is just the combination of egg and sperm outside. Therefore, complications that occur in women who become pregnant naturally will also occur in in vitro fertilization. Therefore, in vitro fertilization may also lead to hydatidiform mole, and hydatidiform mole must be treated in time.

Children are the hope of every family, so for pregnant women, every move of the fetus in their belly will affect the hearts of the whole family. But not every family is so lucky. Many pregnant women have to terminate their pregnancy because of hydatidiform mole. Therefore, we must learn more about the disease of hydatidiform mole and learn the treatment methods in case of emergency.

The chance of deformity in test-tube babies is higher than that in ordinary babies, which has a lot to do with the mother's endocrine system, living environment, and food pollution. Therefore, after the IVF transplant, you need to pay close attention to the baby's condition, go to the hospital for regular check-ups, detect abnormal conditions in a timely manner, and take effective measures to deal with them.

The best treatment for hydatidiform mole is uterine curettage. After the patient is diagnosed with hydatidiform mole, the pregnancy should be terminated immediately and a uterine curettage should be performed immediately. It is best to use a suction uterine surgery with less damage and bleeding, because curettage is likely to cause heavy bleeding. If the patient is older and has no fertility requirements, a hysterectomy can be performed to prevent recurrence.

Postoperative care for hydatidiform mole is very important. After the surgery, the patient should rest in bed and avoid physical activity. Sexual intercourse is prohibited within one month, and pregnancy cannot be achieved again within the next two years. Effective contraceptive measures must be taken during this process. Before hcg turns negative, you need to go to the hospital for check-ups every week. You can reduce the frequency of check-ups after it returns to normal.

In short, for test-tube babies, due to maternal endocrine, food pollution and environmental factors, it is more likely for the fetus to have malformations, so we must pay more attention, go to the hospital for regular check-ups, detect fetal abnormalities in time, and take effective countermeasures as soon as possible to ensure the baby's healthy birth.

What causes hydatidiform mole?

The true cause of hydatidiform mole is unknown. Case-control studies have found that the occurrence of hydatidiform mole is related to nutritional status, socioeconomic status and age. Age is a significant related factor in etiology. The incidence of hydatidiform mole in women over 40 years old is 10 times higher than that in young women. Women under 60 years old are also a high-risk factor for complete hydatidiform mole. Women in these two age groups are prone to fertilization defects. Partial hydatidiform mole has nothing to do with maternal age.

Cytogenetic and pathological studies have shown that the two types of hydatidiform mole have their own genetic characteristics. The chromosomal genome of a complete hydatidiform mole is of paternal origin, that is, it develops from the ovum in the absence of an oogonium or inactivation of the oogonium and from the fusion of the spermatogonium. The chromosome karyotype is diploid, 90% of which are 46,XX. It is formed by the fertilization of an empty egg (an egg without genetic material) and a haploid sperm (23, X). It replicates itself and recovers to diploid (46,XX), and then grows and develops. This is called empty egg fertilization. A minority of them have a karyotype of 46, XY, which is caused by two sperm with different sex chromosomes (23, X and 23, Y) fertilizing an empty egg at the same time, which is called dizygotic fertilization. The karyotype of partial hydatidiform mole is often triploid, 80% of which are 69,XXY, and the rest are 69,XXX or 69,XYY. It comes from the fertilization of a normal egg with two sperm, thus bringing an extra set of paternal chromosome components; it can also be caused by the combination of a normal haploid egg (or sperm) and a diploid gamete that has failed meiosis.