Signs and symptoms of hydatidiform mole

Mole is a very common ectopic pregnancy. There are many factors that induce mole. Women with mole will not only be affected in health, but also may threaten their lives. However, many people do not know much about mole in life. In fact, the symptoms of mole are generally different from those of normal pregnancy. What are the symptoms and signs of mole?

What are the reactions and symptoms of hydatidiform mole?

1. Vaginal bleeding after menopause

Most patients experience irregular vaginal bleeding 2 to 4 months after amenorrhea. The amount is small at first and can easily be misdiagnosed as threatened abortion. The bleeding will gradually increase and often occur repeatedly. Sometimes blister-like tissue will be discharged naturally, which may lead to shock or even death.

2. Abdominal pain

When the molar pregnancy grows rapidly and the uterus expands rapidly, it can cause lower abdominal distension and pain. When the molar pregnancy is about to be expelled, there will be paroxysmal pain in the lower abdomen due to uterine contractions.

(1) Abnormal enlargement and softening of the uterus

Due to villous edema and intrauterine blood accumulation, the uterus of most patients with hydatidiform mole is larger than the normal pregnancy uterus of the corresponding month and has a softer texture. In 1/3 of patients, the size of the uterus matches the month of menopause. Only a few cases are younger than the menopausal month, which may be due to the degeneration and cessation of development of the blisters.

(2) Symptoms of vomiting during pregnancy and pregnancy-induced hypertension

Because the proliferating trophoblastic cells produce a large amount of HCG, vomiting is often more severe than in normal pregnancy. Because the uterus of patients with hydatidiform mole grows rapidly and the tension in the uterus is high, pregnancy-induced hypertension syndrome may occur in the middle and early stages of pregnancy, and even acute heart failure or eclampsia may occur.

(3) Ovarian lutein cyst

Due to the stimulation of large amounts of HCG, patients with hydatidiform mole often develop multiple cysts on one or both ovaries. Generally no symptoms occur, but acute torsion occasionally causes acute abdominal pain. Lutein cysts may regress on their own after the hydatidiform mole is removed. Flavin cysts can store a large amount of HCG. Therefore, after the expulsion of hydatidiform mole and the patient with a giant flavin cyst, the disappearance of HCG in the blood and urine is slower than that of ordinary patients.

(4) Hyperthyroidism: A small number of patients with hydatidiform mole develop mild hyperthyroidism with elevated plasma thyroxine concentrations, but only about 2% develop obvious signs of hyperthyroidism. Symptoms disappear rapidly after the hydatidiform mole is cleared.

Can hydatidiform mole be cured?

Under normal circumstances, after the hydatidiform mole is emptied, serum hCG decreases steadily. The average time for the first drop to normal is 9 weeks, and the longest time is no more than 14 weeks. If hCG remains abnormal after the mole is evacuated, gestational trophoblastic tumor should be considered. High-risk hydatidiform mole should be considered when the following high-risk factors are present: hCG>100,000U/L; the uterus is significantly larger than the corresponding gestational age; the diameter of the ovarian luteinized cyst is>6 cm or bilateral luteinized cysts; age <20 years or >40 years; small hydatidiform mole; history of repeated hydatidiform mole; pregnancy complications: hyperemesis gravidarum, hyperthyroidism, etc.