Can endometrial cancer be cured?

The incidence of endometrial cancer is second only to cervical cancer. It is a malignant tumor with a relatively high incidence rate. It is particularly harmful to women's health. For this disease, early detection and early treatment are necessary. There are many treatment methods. Surgery is the first choice. Through surgical treatment, radiotherapy and chemotherapy are assisted. In daily life, we should also emphasize nutrition, conditioning and health care.

1. Surgical treatment is the preferred method. Patients in stage I should undergo extrafascial hysterectomy and bilateral salpingo-oophorectomy, while patients in stage II should undergo extensive hysterectomy and pelvic lymph node dissection. Surgery can remove the cancerous uterus and other lesions that may have metastasized, including the closely adjacent ovaries, fallopian tubes, and surrounding lymph nodes. Through surgery, the tumor can be directly eradicated to achieve the purpose of cure, or the tumor size can be reduced to benefit the patient's prognosis. Second, surgery allows for the correct diagnosis and staging of the disease. Although most patients with endometrial cancer have undergone segmental curettage, the error rate in pathological type and degree of differentiation between curettage specimens and those after hysterectomy is as high as 20%. These indicators are directly related to further postoperative treatment and prognosis. Therefore, accurate clinical staging is the guarantee for choosing appropriate treatment, otherwise it is very likely to lead to excessive or insufficient treatment.

2. For patients in stage I who receive combined surgery and radiation therapy, if cancer cells are found in the ascites or the muscularis is infiltrated, or there is lymph node metastasis, external beam irradiation may be used after surgery. For stage II or some stage III patients, external beam radiation or intracavitary radiation therapy is added before surgery, and surgery is performed 1 to 2 weeks after the end of radiotherapy.

3. Radiotherapy: The elderly, frail patients, patients with severe medical complications who cannot tolerate surgery, and patients in stage III or above who are not suitable for surgery can be treated with radiotherapy, including intracavitary and external irradiation.

4. Hormone therapy for young early-stage patients who wish to retain their fertility, patients with advanced cancer who cannot undergo surgery or patients with cancer recurrence, can be treated with large doses of artificially synthesized progestins. Such as 400 mg of medroxyprogesterone acetate, intramuscular injection, 2 to 3 times a week; 500 mh of progesterone acetate, intramuscular injection, 2 to 3 times a week, etc. The efficacy of the treatment can only be evaluated after at least 12 weeks.