Can high prolactin lead to pregnancy? Infertility should be taken seriously

The most typical manifestation of high prolactin is infertility in women. This disease will affect ovulation, so it is necessary to treat it in time. To treat high prolactin, you can choose symptomatic treatment of Western medicine, find the cause of the disease, and do treatment to promote ovulation.

1. High prolactin can cause infertility

70.71% are primary or secondary, caused by anovulation, corpus luteum deficiency or luteinized unruptured follicle syndrome (LUFS).

2. Western medicine treatment of hyperprolactinemia

1. Treatment of the cause and primary disease

For example, eliminate adverse mental stimulation, stop taking HPRL-inducing drugs, and actively treat primary diseases such as pituitary tumors, hypothyroidism, Cushing's disease, etc.

2. Anti-prolactin-bromocriptine therapy

Bromocriptine is a semi-synthetic ergoline derivative and a dopamine receptor agonist. It can promote the synthesis and secretion of PRL-IH and inhibit the synthesis and release of PRL through the receptor mechanism. It also directly acts on pituitary tumors and PRL cells to curb tumor growth and inhibit the secretion of PRL, GH, TSH and ACTH.

Bromocriptine therapy is suitable for all types of HPRL and is also the first choice for pituitary adenomas (micro/macroadenomas), especially for young infertile women who hope to have children. The dosage is 2.5-7.5 mg/d, orally. Other anti-prolactin drugs include: Levodopa (Levo-Dopa), octahydrobenzoquinoline (CV205-502), vitamin B6, etc. See the Anti-prolactin section in the Endocrine Therapy chapter for details.

3. Ovulation induction therapy

It is suitable for patients with HPRL, anovulatory infertility, and those who cannot successfully ovulate and become pregnant after simple bromocriptine treatment. That is, a comprehensive therapy with bromocriptine as the main drug and other ovulation-inducing drugs in combination: ① bromocriptine-CC-hCG; ② bromocriptine-hMG-hCG; ③ GnRH. Pulse therapy - bromocriptine, etc. Combined therapy can save antiprolactin, shorten the treatment cycle and improve the ovulation rate and pregnancy rate.