Pay attention! Ovarian germ cell tumors occur primarily in young women

Ovarian germ cell tumors are a special group of gonadal tumors that are more common in children and adolescents. Patients generally experience abdominal pain, bloating, frequent urination, constipation, etc. The ovaries are extremely important for women, so we must pay attention to the care of the ovaries in daily life.

Morbidity and Mortality:

Ovarian germ cell tumors are uncommon but highly aggressive and often occur in young women and adolescent girls. The tumor usually occurs on one side and is usually curable if detected early. The combination of surgery and postoperative chemotherapy can significantly improve the patient's prognosis.

Dysgerminoma:

Studies have shown that the 10-year survival rate after conservative surgery for patients with dysgerminoma that is confined to the ovary, has a diameter of less than 10 cm, has a complete and smooth surface, is not adhered to other organs, and has no ascites is 88.6%; many patients can still become pregnant after unilateral salpingo-oophorectomy. Even patients with incomplete resection of dysgerminomas have been able to remain disease-free following subsequent chemotherapy with bleomycin, etoposide, cisplatin (BEP) or a combination of cisplatin, vinblastine, and bleomycin (PVB).

Other germ cell tumors:

According to a study, among 35 patients with germ cell tumors, half of whom had advanced, recurrent or progressive tumors, 97% of the patients achieved remission for up to 10-54 months after combined use of BEP. Two other gynecologic oncology research groups reported that 89 of 93 patients with stage I, II, and III disease were cured after tumor resection and three courses of BEP.

Ovarian endodermal sinus tumor is also an aggressive tumor. A literature report before the use of combination chemotherapy showed that only 27% of 96 stage I patients were still alive 2 years after diagnosis. 50% of patients die in the year of diagnosis. Patients with more mature teratomas generally survive longer, but the survival rate of patients with immature teratomas after surgery depends on the grade of the tumor. Before the advent of modern chemotherapy, among 58 patients with immature teratomas, 18% of patients with stage 1 relapsed, 37% of patients with stage 2 relapsed, and as high as 70% of patients with stage 3 relapsed.