The failure of women to ovulate will directly lead to infertility, so what is the situation of female ovulation? It is a physiological phenomenon unique to women and changes periodically. Normally, it comes once a month. It is mainly maintained by the hypothalamus, pituitary gland, and ovaries. Therefore, any cause that leads to dysfunction of the hypothalamic pituitary axis, abnormal feedback mechanism, and ovarian lesions can cause ovulation disorders. (1) Turner syndrome and simple gonadal dysgenesis are chromosomal abnormalities that both present with primary amenorrhea as the main clinical manifestation, with elevated gonadotropin and decreased estrogen. (2) Premature ovarian failure and ovarian antagonism syndrome: Hypergonadotropic amenorrhea caused by ovarian failure before the age of 40 is called premature ovarian failure. Women with primary amenorrhea or secondary amenorrhea before the age of 30 have elevated levels of endogenous gonadotropin and normal follicles in their ovaries, but are low-responsive to high-dose exogenous gonadotropin stimulation. This is called ovarian insensitivity syndrome or ovarian antagonism syndrome. (3) Polycystic ovary syndrome: often manifested as amenorrhea or infrequent menstruation, long-term anovulation, excessive androgen, and no cyclical fluctuation of estrogen. (4) Unruptured luteinized syndrome: In a normal menstrual cycle, an ovarian follicle develops into a dominant follicle, but the follicle does not disappear or continues to grow 48 hours after the LH peak during ovulation, and persists for several days. The granulosa cells have become luteinized, but the follicle has not ruptured. The basal body temperature (BBT), cervical viscosity and endometrial changes of LUFS are similar to normal ovulation, giving the illusion of ovulation. It is one of the causes of infertility and one of the reasons why the pregnancy rate of clomiphene-induced ovulation is low. The above are the causes of female ovulation disorders. When a woman does not ovulate, she should be examined in time, and a diagnosis and treatment plan should be made based on relevant examination results. Women's health is very important and needs more care. In any case, female friends should always prevent these diseases. |
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