Gynecological liquid-based thin-layer cytology examination

In recent years, an intelligent cervical cytology acid-fast staining technology, namely liquid-based cytology test (TCT for short) has been increasingly widely used in cervical cytology screening. The TCT test uses a liquid-based cytology detection network to detect cervical cells and conducts the internationally used TBS cytology classification diagnosis. It is currently the most advanced cytology examination technology in the world. Compared with the traditional cervical scraping Papanicolaou acid-fast staining test, it has significantly improved the satisfaction rate of specimen collection and the diagnosis rate of abnormal cervical cells. The diagnosis rate of TCT test for cervical tumor cells is close to 100%.

In addition, liquid-based cytology examination can also detect precancerous lesions and microbial species such as fungi, Trichomonas, and mycoplasma. Currently in Europe and the United States and in my country's first- and second-tier cities, TCT technology has been used to screen for cervical cancer in women.

The traditional acid-fast staining method has a false negative rate of 2% to 50%. In addition to the fact that the eye fatigue and the smeared cells are not of the same level, which affects the diagnosis, the acid-fast stain contains a large amount of blood cells, white blood cells, mucus and fallen necrotic tissue, which affects the correct diagnosis. In order to solve the latter problem, cell engineering experts have recently developed a new technology called liquid-based chromatographic cytology, which uses technical methods to remove residues on the acid-fast stain and directly produce clearly observable chromatographic acid-fast stain. The basic method is to collect the cell storage fluid, filter the fluid through proportional fluid, separate the mucus, blood and inflammatory cells in the specimen by natural ion exchange, and collect the remaining squamous epithelial cells to make a 13mm diameter superchromatographic cell on a coverslip.

48 specimens can be collected at the same time each time, and cell staining can be carried out simultaneously in the automatic production process, achieving higher quality and higher efficiency. This will make it easier for cytologists to observe every line of sight, thereby significantly reducing the false negative rate. It makes it easier for readers to observe and its diagnostic accuracy is higher than the traditional method.