Can medroxyprogesterone acetate tablets delay menstruation?

Can medroxyprogesterone acetate tablets delay menstruation?

Menstruation refers to the phenomenon that tissue and blood after the endometrium falls off are discharged from the vagina, and the flowing blood is called menstruation. Generally speaking, women and some female mammals will have regular menstruation during their reproductive period, so this cycle is called menstruation. But now some people want to use medicine to delay menstruation. For example, medroxyprogesterone acetate tablets. Can medroxyprogesterone acetate tablets really delay menstruation? Today I will explain to you whether medroxyprogesterone acetate tablets can delay menstruation.

The English name of medroxyprogesterone acetate tablets: Medroxyprogesterone Acetate Tablets Chinese Pinyin: Cusuan Jiaqiangyuntong Pian Main ingredients and their chemical names: The main ingredient is medroxyprogesterone acetate. Its chemical name is: 6α-methyl-17α-hydroxypregnane-4-ene-3,20-dione acetate. Its structural formula is: Molecular formula: C24H34O4, molecular weight: 386.53

【Properties】White tablets.

[Pharmacology and Toxicology] Progestogen drugs act on the endometrium, can promote the proliferation and secretion of the endometrium, inhibit the release of luteinizing hormone from the anterior pituitary through negative feedback on the hypothalamus, and inhibit the ovulation process of the ovary.

The anticancer effect may be related to the anti-estrogen effect.

[Pharmacokinetics] After oral administration, it is absorbed in the gastrointestinal tract and degraded in the liver. Peak blood concentration is reached 2 to 3 days after intramuscular injection. The higher the peak blood drug level, the faster the drug is cleared. The drug cannot be detected in the blood until 6 to 9 months after intramuscular injection of 150 mg. When the blood level of medroxyprogesterone acetate exceeds 0.1 mg/ml, both luteinizing hormone (LH) and estradiol are inhibited, thereby inhibiting ovulation.

[Indications] It can be used for irregular menstruation, functional uterine bleeding and endometriosis, etc. It can also be used for advanced breast cancer and endometrial cancer.

[Usage and Dosage] 1. Functional amenorrhea: oral, 4-8 mg per day, for 5-10 consecutive days; 2. Endometrial cancer: oral, 100 mg at a time, 3 times a day, or oral 500 mg, 1 to 2 times a day, as a maintenance dose after intramuscular injection.

[Adverse Reactions] Some women experience irregular bleeding. When treating tumors, high therapeutic doses may cause Cushing's-like symptoms. Long-term use may cause abnormal liver function.

[Contraindications] This product is contraindicated in patients with impaired liver and kidney function, patients with a history of thrombosis such as cerebral infarction, myocardial infarction, thrombophlebitis, undiagnosed bleeding from sexual organs, urinary tract bleeding, or a history of allergy to this product.

[Precautions] Use with caution if you have heart disease, epilepsy, depression, diabetes, migraine, or asthma.

[Use in pregnant and lactating women] Prohibited.

[Use in Children] Use with caution.

[Drug Interactions] This product can be used in combination with chemotherapy drugs to enhance their anti-cancer effects. Combination with adrenocortical hormones may promote thrombosis

The above is the article about whether medroxyprogesterone acetate tablets can delay menstruation. However, it is still recommended that you take medication to delay menstruation if there are really special circumstances. After all, all medicines are toxic. So if it’s not a serious problem, try not to take medicine.

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