Introduction to ovarian lymphoma

What is ovarian lymphoma? Both the elderly and children are well aware of the dangers of lymphoma, but they may not know what ovarian lymphoma is. We all know that lymph nodes are distributed throughout our body, and once lymph nodes become diseased, they will turn into lymphoma. Moreover, lymphoma is very harmful and metastasizes very quickly, so the treatment of lymphoma must be carried out at the best time. If missed, it will bring great danger to the patient's family and life. Ovarian lymphoma is a more dangerous member of the lymphoma family. So what is ovarian lymphoma?

Primary ovarian lymphoma (POL) is very rare, accounting for 0.04% to 0.5% of all ovarian malignancies. 3%, mostly case reports and retrospective summaries. According to domestic reports, POL accounts for 1.2% to 1.4% of extranodal lymphoma, while in Europe and the United States it only accounts for 0 to 0.3%. The number of reports of this disease has increased in recent years, which may be related to the further improvement of pathological diagnostic technology.

Most of the POL cases reported so far are non-Hodgkin's lymphoma, with diffuse large B-cell type being the most common, while reports of Hodgkin's lymphoma are rare. POL can occur unilaterally or bilaterally, with bilateral disease accounting for 48.2% to 52.4%, with the right side being more common than the left side. The disease is usually diagnosed in the middle or late stages, mainly in stages III and IV. POL is highly malignant and has a poor prognosis.

The disease is most common between the ages of 30 and 40, when women are at their peak childbearing age. It is speculated that the cause of the disease may be related to the vigorous ovarian function during this period, which makes it easy to get a viral infection, but the specific cause needs further study.

2. Clinical manifestations

Ovarian lymphoma often occurs before menopause. The clinical manifestations are nonspecific. There may be no symptoms in the early stages, and a pelvic mass may occasionally be palpated. In the later stages, symptoms such as abdominal distension, abdominal pain, ascites, irregular menstruation, vaginal bleeding, and amenorrhea often occur. Symptoms such as fever, weight loss, night sweats, bone and joint pain, and lower limb edema may also occur. Ovarian lymphomas are rarely asymptomatic and are discovered incidentally during a physical examination.

The vast majority of ovarian lymphomas are bilateral, and the lesions can range from the size of a normal ovary to a larger mass (up to 20 cm in diameter). POL may also involve the fallopian tubes, uterine serosa, omentum, mesentery, abdominal wall, pelvic wall, intestinal wall, appendix, para-aortic lymph nodes, and pelvic lymph nodes. In late stages, the tumor may affect the kidneys, pancreas, stomach and other organs.

Because of its low incidence and nonspecific clinical manifestations, this disease can be easily diagnosed as other types of ovarian malignant tumors.

Case reports have found that ovarian lymphoma can be combined with autoimmune hemolytic anemia, hypercalcemia, Meigsps syndrome, borderline serous sarcoma, ovarian adenocarcinoma, teratoma tumor lysis syndrome, etc.

The above is an introduction to ovarian lymphoma. The harm of lymphoma is particularly great, so female friends must pay attention to maintaining their ovaries in daily life, go to the hospital for regular check-ups, and understand their physical condition. We hope our introduction can be helpful to you. I also wish all female friends good health and lasting beauty!