Contraindications before and after HPV vaccination

Cervical cancer is one of the main malignant tumors that endanger the health and life of female residents in my country. With the in-depth study of cervical cancer and its cause HPV, HPV vaccine has finally been approved for sale in China. We can prevent cervical cancer! Today, Professor Di Jiangli, director of the office of the Maternal and Child Health Center of the Chinese Center for Disease Control and Prevention, will introduce you to this friend who has come from afar.

What is the HPV vaccine?

HPV vaccine contains the key capsid protein L1 of the HPV virus, which can assemble itself into similar HPV virus-like particles (VLPs). These particles do not contain viral genetic material and therefore cannot reproduce, in other words, they are not infectious, but they can induce the body to produce specific antigens. HPV vaccines are divided into protective vaccines and therapeutic vaccines. All HPV vaccines currently on the market are protective vaccines.

There are three protective vaccines worldwide, namely the HPV vaccine for HPV types 16 and 18, which were launched in 2006, 2007 and 2014 respectively, the HPV vaccine for HPV types 6, 11, 16 and 18, and the HPV vaccine for HPV types 6, 11, 16, 18, 31, 33, 45, 52 and 58. At present, our country has approved the sale of the first two vaccines, both of which cover the two high-risk HPV types HPV16 and 18, and can cover more than 70% of cervical cancer.

How to get the HPV vaccine?

The best way to prevent cervical cancer is to get the protective HPV vaccine. Currently, all HPV vaccines sold in my country require a three-dose vaccination program.

It is very important to emphasize that most people are likely to be infected with HPV in their lifetime, so women who have had sexual activity are at potential risk of cervical cancer. In addition, women who have never undergone cervical cancer screening are also key targets for cervical cancer. It should be noted that people who are persistently infected with high-risk HPV have a higher risk of cervical cancer.

People who have had sex too early, have multiple sexual partners or have sexual partners with multiple sexual partners, have sexual partners with a history of cervical cancer, have reproductive organ cancer, have multiple pregnancies, have multiple births, have other reproductive tract infections, are infected with HIV, smoke or take drugs, take long-term contraceptives, have malnutrition, have a family history, have low immune function, have experienced cervical epithelial cell disease, have a history of vaginal cancer, and belong to the middle- and low-income groups, are all key targets for cervical cancer.