Is it true that the lower the blood uric acid level, the better?

Is it true that the lower the blood uric acid level, the better?

For gout patients, blood uric acid levels must be strictly controlled. Long-term control of blood uric acid levels to < 360 µmol/L can not only dissolve urate crystals, reduce the number and size of crystals, but also prevent the formation of new crystals.

For patients with concomitant tophi, the guidelines recommend a serum concentration below 300 μmo/L.

Serum uric acid is a natural antioxidant in the body that can protect the nervous system and enhance human immunity.

Low blood uric acid levels may increase the risk of neurological diseases such as Alzheimer's disease and Parkinson's syndrome. Therefore, the lower the blood uric acid level, the better!

The truth: For patients with asymptomatic hyperuricemia, the lower the blood uric acid level, the lower the incidence of gout, but the lower the blood uric acid level is not necessarily better. It is generally recommended that the target level for lowering uric acid should not be lower than 180 μmol/L.

The chronic disease and risk factor monitoring data in my country in 2018 showed that the prevalence of hyperuricemia among adult residents in my country reached 14.0%, and the prevalence among young men (18-29 years old) reached 32.3%, showing a significant trend of getting younger.

There is still a long way to go from high uric acid to gout attacks. Reasonable diet control, proper exercise, and standardized drug treatment can keep uric acid at the standard level for a long time and reduce the number of gout attacks.