Egg, Ji Xiaobao's past and present life

Previous life

Ji Xiaobao's previous life was Sister Egg, who lived in a palace filled with fluid (follicle), growing slowly and gradually maturing. Under normal physiological conditions, only one qualified sister in one palace can get married every month, and the other palaces (follicles) are suppressed in various ways and closed down.

However, in the "IVF" treatment, in order to obtain more usable eggs in a month, "superovulation" treatment is generally required. That is, to make multiple palaces grow and develop, and cultivate a group of qualified young ladies. The growth and development of each palace depends on various drugs that promote ovulation.

Marry

Before Ji Xiaobao was born, he had to become a qualified egg. The egg-bearing ladies who were to be married were taken out in the palace through an egg-collecting needle, and were selected again to remove the immature eggs that were mixed in. Then they were bathed, changed clothes, and prepared to be married.

Encounter

The egg lady, who is about to get married, is ready to go. Finally, she meets her other half, the sperm man, in a "specific place" - a petri dish. The process of getting to know each other and combining with the sperm man is fertilization.

There are two ways to meet:

1) Take the initiative: (conventional in vitro fertilization IVF): Some sperm buddies are more vigorous and take the initiative to attack. The egg buddies and the sperm buddies can choose freely and fall in love with each other before successful fertilization can occur.

2) Passive acceptance: (Intracytoplasmic Sperm Injection (ICSI): Some sperm guys are shy and need embryologists to act as matchmakers to help egg girls choose suitable partners, so that they can eventually get together successfully.

4. This life

Once the hand-holding is successful, an embryo will be formed - Ji Xiaobao. The palace where Ji Xiaobao is born is the incubator. If the egg sister and the sperm brother successfully combine, it is the beginning of the birth of Ji Xiaobao. At this time, the egg sister is branded (pronucleus, normal fertilization has two pronuclei), and is officially upgraded to a fertilized egg. However, in special circumstances, such as abnormal morphology of the egg sister and the sperm brother or problems with the environment of the meeting place, abnormal fertilization occurs, such as: (1) No pronucleus is seen, it cannot divide, and fertilization fails; (2) Three or more pronuclei appear, in which case the fertilized egg will be eliminated; (3) One pronucleus appears, in which case the probability of abnormal fertilized egg is also relatively high, and it can be continued to be cultured and observed before deciding to abandon it.

Ji Xiaobao needs to stay in the incubator for 3 to 6 days before he can upgrade again.

5. Election

1) Cultivate Ji Xiaobao for 3 days

Since the fertilized egg, Ji Xiaobao has been working hard to develop. But this batch of Ji Xiaobao still has to go through a series of elections before they can be finally selected and get a ticket for a luxurious tour of the womb.

The criteria for evaluating whether Ji Xiaobao is excellent are mainly based on appearance (looking at the developmental morphology of the embryo, whether there are fragments, whether there are unequal divisions, and whether the number of divided cells is appropriate. Embryologists are the final judges)

2) Raise Ji Xiaobao for 6 days

Sometimes, after 3 days of cultivation, the Ji Xiaobaos look very similar and cannot be distinguished by face recognition. They need to continue to be cultivated until the 5th or 6th day, when they are upgraded Ji Xiaobao - blastocysts. The Ji Xiaobao who can develop into blastocysts will have a much higher chance of success. Of course, when they reach the blastocyst stage, they need to scan their faces again (still judged by the embryologist mentor team). In the end, the carefully selected Ji Xiaobao will get a cruise trip to take a luxury tour of the uterus.

3) Selection: (Preimplantation chromosome screening PGS): Some egg sisters or sperm brothers have some defects, but they cannot be distinguished from the outside. The problem is discovered after the combination. In order for Ji Xiaobao to successfully complete the luxurious tour of the uterus, a more in-depth review (chromosome or gene screening) must be carried out to select the qualified Ji Xiaobao to be transplanted into the uterus.

6. The Sleeping Ji Xiaobao

Of course, not all carefully selected Ji Xiaobao can take the Uterus Luxury Cruise at the same time. The Uterus luxury cruise ship can only allow up to 2 Ji Xiaobao to board the ship at the same time. Therefore, the Ji Xiaobao who got the ticket but failed to board the ship can only temporarily enter the freezer (-196℃ liquid nitrogen tank) to rest (embryo freezing). When the Uterus Cruise sets sail again, they will be awakened and board the ship with their tickets.

Ji Xiaobao wakes up

The uterus cruise ship docked again, and Ji Xiaobao needed to be awakened to board the ship (embryo resuscitation). At this time, Ji Xiaobao slowly woke up from the freezer, took a bath, changed clothes, took the bed ticket, and got ready to embark on the luxurious journey of the uterus.

A luxurious tour of Xiaobao's womb

Holding the boat ticket and singing a little tune, Ji Xiaobao started his official uterine luxury tour (embryo transfer). First, Ji Xiaobao had to walk around in the uterine cruise cabin, find a suitable place to settle down, and then eat all kinds of cruise meals (to absorb nutrients), growing and growing, until one day, he got too fat and his clothes burst, and then he arrived at his destination steadily. After finishing the uterine luxury tour, Ji Xiaobao has been upgraded to a dominant baby, born, and completed his mission in past and present lives.