Most granules are dissolved in boiling water and taken, but some granules need to be taken orally or swallowed. For example, L-glutamine sodium guarenate granules are taken orally, and water should be avoided. Because the drug is a gastric mucosal protective agent, it needs to form a protective layer in the stomach after taking it to exert its therapeutic effect. Taking it after dissolving it in water will affect the drug effect. Mesalazine sustained-release granules for the treatment of ulcerative colitis are also swallowed. The granules need to be poured into the mouth and then taken with water. The reason is that if the drug is taken with water, it will be quickly absorbed by the upper gastrointestinal tract after dissolving it in water, and the sustained-release effect will be lost. The drug cannot be released in the distal ileum and colon to exert its effect. Another example is montelukast sodium granules, which are taken orally and mixed with a spoonful of soft food at room temperature or cold (such as applesauce) or infant formula or breast milk. This is because montelukast sodium is sensitive to light and will be converted into substances that are ineffective for treatment after exposure to light. Therefore, it cannot be dissolved in water or other liquids with poor light-shielding properties, but you can drink water after taking the medicine. |
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