When taking aspirin for a long time, under what circumstances should you stop taking the drug?

Aspirin is a commonly used drug for preventing cardiovascular and cerebrovascular diseases. But some friends always ask Huazi that they heard that taking aspirin for a long time will cause adverse reactions, but doctors also say that you can't stop taking the drug casually, otherwise the protective effect of the drug will be lost.

Huazi said that what the doctor said was correct. Aspirin should not be discontinued easily, but it does not mean that it cannot be discontinued. When serious adverse reactions occur, it is necessary to stop taking it.

1. Aspirin is a "double-edged sword" Aspirin is a "magic drug" for mankind. For more than a hundred years, people have used large doses of aspirin to relieve fever, relieve pain, and fight rheumatism, helping people stay away from pain. Now, small doses of aspirin are mainly used to inhibit platelet aggregation, prevent the formation of blood clots, and avoid cerebral infarction and myocardial infarction.

The pharmacological mechanism of aspirin is to bind to cyclooxygenase on platelets and produce an inhibitory effect. However, cyclooxygenase is also present in other tissues of the human body and will also be inhibited by aspirin, which will lead to a decrease in the production of prostaglandins that protect the digestive tract, thereby weakening the barrier function of the digestive tract mucosa and making it more susceptible to damage.

Aspirin will not cause blood vessels to rupture, but it will weaken the coagulation function of platelets, so when blood vessels are damaged, the healing time will be prolonged. To a certain extent, it may increase the risk of spontaneous bleeding, the most dangerous of which is cerebral hemorrhage.

Huazi often says that aspirin treatment is a "double-edged sword". While treating the disease, it also brings risks. It is only recommended to use it when the benefits of the medication far outweigh the risks. During the medication period, adverse reactions need to be monitored. If abnormalities occur, it is likely that the medication needs to be suspended.

2. Several situations in which you need to stop taking aspirin 1. Allergy: Some people may be allergic to aspirin or have asthma attacks when taking aspirin and need to stop taking aspirin.

2. Digestive tract damage: Long-term use of aspirin may cause digestive tract damage, induce gastric ulcers or aggravate existing ulcers. During medication, observe whether there is abdominal pain, bloating, etc. If it occurs, seek medical attention in time. If a digestive tract ulcer occurs, you need to stop taking the medicine.

3. Black stools: Severe damage to the digestive tract mucosa can cause bleeding. If the amount of bleeding is large, tarry black stools will appear. However, it should be noted that similar black stools will appear after eating blood sausage and blood tofu, so be careful to distinguish. If the amount of gastric bleeding is small, it may not cause a change in stool color. It is recommended to do regular stool examinations. If occult blood is found, it is recommended to suspend medication for treatment.

4. Thrombocytopenia: Regular blood tests should be performed during medication, and attention should be paid to the number of platelets. Aspirin works by binding to platelets, but when the number of platelets is low, the coagulation function will further decline. At this time, the dose of aspirin needs to be reduced. Those with severe low platelet counts need to stop taking the medication and find out the cause of the low platelet count. If surgery is required, the medication needs to be stopped 7 days in advance to reduce intraoperative bleeding.

5. Coagulation disorder: The blood coagulation of the human body is not only a process of platelet aggregation, but also involves multiple coagulation factors. It is recommended to check the coagulation time regularly. If abnormal coagulation factors are found, or if it needs to be used in combination with anticoagulants, aspirin may need to be reduced or discontinued to reduce the risk of bleeding diseases.

6. Poor blood pressure control: Hypertension is the main risk factor for cerebral hemorrhage. If blood pressure cannot be stably controlled below 160 mmHg, the use of aspirin is not recommended.

3. Continue to take the medicine after the adverse reaction is eliminated. After finding out the cause and eliminating the adverse reaction of aspirin, you need to resume taking the medicine as soon as possible. Because most of the risk factors for cardiovascular and cerebrovascular diseases are atherosclerosis, which cannot be completely eliminated, continuous medication is needed to effectively prevent the occurrence of the disease.

During the medication process, it is necessary to take the medication every day. It is not recommended to take it on and off. Because the human body's platelets are renewed by about 15% every day, if the medication is stopped for more than 48 hours, the protective effect will disappear. If you cannot tolerate the adverse reactions of aspirin, you can use gastric mucosal protective drugs under the guidance of a doctor, or replace it with other antiplatelet drugs.

In summary, aspirin is a "double-edged sword" with both benefits and risks. It can prevent the formation of blood clots, but it may also cause adverse reactions. It can only be used when the benefits far outweigh the risks. When using it, if serious adverse reactions occur, you can suspend the medication under the guidance of a doctor. If you have any questions about medication, please consult a doctor or pharmacist in time. I am pharmacist Huazi. Welcome to follow me and share more health knowledge.