When using flupentixol and melitracen to treat anxiety and depression, pay attention to individual differences

A netizen left a message to Huazi, saying that he suffers from anxiety and depression and is currently taking flupentixol-melitracen. He asked Huazi if he could tell him what he should pay attention to when taking this medicine?

Hua Zi said that the drug he took was a compound preparation of flupentixol and melitracen. From the perspective of pharmacological classification, flupentixol is an antipsychotic drug of the thioxanthene class, and melitracen is a tricyclic antidepressant. After forming a compound preparation, it is used to treat depression, anxiety and emotional apathy. However, during treatment, individual differences are large, and not everyone can achieve the desired effect.

1. Treatment of mental illness requires correct diagnosis. For the treatment of anxiety and depression, the first step is to make a correct diagnosis. Some people have "negative symptoms" of mental disorders, which are manifested as indifference, lack of desire, and unwillingness to communicate with others. The cause is abnormal activation of dopamine nerves in the brain.

Patients with depression will show symptoms of low mood and reduced speech, and are almost always accompanied by anxiety. The reason is an imbalance of neurotransmitters such as serotonin and norepinephrine in the brain.

The two have similar symptoms, but the causes are different nervous system problems, and professional psychiatrists are needed to correctly diagnose and choose targeted drugs for treatment. Otherwise, the wrong medication may aggravate the symptoms.

2. What are flupentixol and melitracen? Flupentixol can block dopamine receptors and has certain anti-adrenal and anti-cholinergic effects, but they are weaker. It can produce anti-depressant and anti-anxiety effects, but it is classified as an antipsychotic drug and is suitable for schizophrenia, anxiety neurosis and menopausal depression accompanied by obsessive-compulsive state or anxiety and depression.

However, it may also aggravate depression and anxiety symptoms, and even induce suicidal adverse reactions. Moreover, due to the inhibition of dopamine receptors, it may cause drug-induced extrapyramidal symptoms (Parkinson's syndrome).

Melitracen is a serotonin reuptake inhibitor that can inhibit the reuptake of serotonin by synapses and increase nerve excitability. This can help patients with depression to feel uplifted and excited. However, when used on normal people, it can cause a calming and sleepy effect, and has a poor effect on depression caused by mental disorders.

Melitracen is a tricyclic antidepressant. This type of drug has anticholinergic effects, which can cause blurred vision, dry mouth, constipation and urinary retention. It also affects the cardiovascular system and may cause adverse reactions such as postural hypotension and arrhythmia. It also produces a certain degree of dependence, making it difficult to stop taking the drug.

3. Individual differences in actual application are large. In actual use, the compound preparation of flupentixol and melitracen has received mixed feedback. The two drugs can quickly relieve anxiety and depression through different mechanisms, and the effect is obvious in the early stage of medication. However, with continued use, the efficacy of the drug may decrease, and it may also cause the original symptoms to worsen.

When taking medication for a long time, some patients will continue to achieve good anti-anxiety and anti-depression effects, while the efficacy of some patients will become worse and worse, and there are great individual differences.

Moreover, the drug has many adverse reactions. During the medication period, insomnia may occur, anxiety may be aggravated, adverse cardiovascular reactions may occur, or drug-induced Parkinson's syndrome (such as tardive dyskinesia, tremor, etc.) may occur. Moreover, after long-term use of the drug, it will be more difficult to withdraw the drug.

Huazi's opinion on flupentixol-melitracen is that it can be used in the short term to quickly control the symptoms of anxiety and depression, but long-term use is not recommended. People who are troubled by anxiety and depression should find a professional psychiatrist to make an accurate diagnosis, and then use more targeted drugs for treatment to reduce the adverse reactions of the drugs.

In summary, flupentixol and melitracen are a compound preparation composed of two drugs, which have a good control effect on anxiety and depression. However, when taking the medicine for a long time, individual differences are large. If serious adverse reactions occur, the medicine should be stopped in time and medical treatment should be sought. A professional psychiatrist should adjust the medicine. I am pharmacist Huazi. Welcome to follow me and share more health knowledge.