How long does it take to get the report of amniocentesis?

Amniocentesis is a test that some pregnant women need to undergo. This test can check whether the baby is healthy and enable pregnant mothers to give birth to the baby with peace of mind. Generally, amniocentesis will be performed if the Down syndrome screening fails. However, some beautiful women who have just become mothers do not have a lot of knowledge about pregnancy. For example, how long does it take for the amniocentesis test report to be issued? I believe many people are quite confused. Let's take a look at the detailed explanation.

The results of amniocentesis are usually available 2-3 weeks after the operation, but the actual time to get the results depends on the schedule of the outpatient department of the hospital. Generally speaking, the results of amniocentesis to check whether there are abnormalities in sex chromosomes can be obtained within 2-3 days. This is because the sex chromosome analysis of somatic cells is not like ordinary tests. As long as the amniotic fluid of the pregnant woman is placed in the equipment, the interphase somatic cells are directly fluorescent in situ hybridization is used, and the results can be obtained quickly. However, the cells extracted by amniocentesis must undergo conditioning before they can be broken down to a sufficient number, and this process generally takes about 7-14 days. After that, the sex chromosomes also have to go through the whole process of staining, observation, photography, enlargement, editing, and approval, which takes 2-3 weeks.

The pregnant woman went home to recuperate after the amniocentesis, so there is no need to worry too much. Generally, if the test result is positive, that is, the test result is abnormal, the doctor will inform the pregnant woman as soon as possible. Generally, if there is no notification, it means that the situation is normal and you just need to pick up the result sheet within the promised time.

How to judge the results of amniocentesis

1. Read the narrative

The amniocentesis test report described: The G-banding analysis of the sex chromosomes 400-500 in the amniotic fluid cells of the pregnant woman showed that no trisomy 18, 13, and 21 were found in the analysis. Result analysis: No trisomy 18, 13, and 21 were found, indicating that the sex chromosomes were normal, which means that the child's development was normal.

2. Look at the high alpha-fetoprotein

The amniocentesis report contains a high alpha-fetoprotein (AFP) component, which can usually be used to determine the risk of fetal malformation. Standard value: The AFP value in the amniotic fluid of normal pregnant women reaches its peak at the 13th week of pregnancy, with an average value of 26.303μg/L (26303ng/ml); it decreases faster at the 19th week of pregnancy, and at full-term pregnancy, the average value is 1.266μg/L (1266ng/ml). If the AFP level in the amniotic fluid of a pregnant woman is higher than the average, it indicates that the fetus is likely to be anencephaly or have spina bifida, or may have other malformations, such as congenital kidney disease, esophageal or intestinal atresia, umbilical defect, cystic hygroma, sacrococcygeal teratoma, Rh blood type incompatibility, congenital idiocy, congenital hormone dysplasia, etc.

3. Look at the estriol in the amniotic fluid of pregnant women

Estriol (E3) in the amniotic fluid of pregnant women can accurately reflect the function of the fetal embryo and estimate the prognosis of abnormal fetuses. Result analysis: The E3 value in the amniotic fluid of a normal pregnant woman is more than 100μg/ml. If the analysis sheet shows that E3 is lower than 100μg/ml, it indicates that the prognosis of the fetus is poor.

How to do amniocentesis during pregnancy

Amniocentesis is a form of prenatal examination. Its actual operation steps are as follows:

1. Before announcing the extraction of amniotic fluid from pregnant women, pregnant women should first undergo B-ultrasound examination to determine the size of the fetus, gestational age, fetal position and number of fetuses, and find the most suitable location for needle insertion.

2. Then apply medical alcohol on the pregnant mother's abdomen for disinfection, and place a sterile test sheet with holes under the belly.

3. Use a No. 20 or 22 spinal puncture device and, under the correct guidance of ultrasound, gradually insert it into the previously selected amniotic cavity.

4. Make sure the spinal cord puncture device is in the amniotic cavity, and begin to extract the amniotic fluid with air pressure. The first 2 ml of amniotic fluid must be discarded (to avoid maternal cell contamination).

5. Draw out about 20 ml of the pregnant woman's amniotic fluid and put them into two sterilized test tubes.

6. Pull back the entire puncture device, put gauze on the needle hole on the abdomen, go to the hospital to rest for two hours, and go home if you feel no discomfort.