Down syndrome screening mom value comparison table

Down syndrome screening is one of the mandatory prenatal examination items. It is mainly based on testing the pregnant woman’s blood and comprehensively considering the pregnant woman’s age, weight, weeks of pregnancy and other conditions to infer the probability of the fetus having Down syndrome. So, what is the mom value for Down syndrome screening? The editor below will introduce the indicators of Down syndrome screening to everyone. It is recommended that pregnant women seek advice from their doctors after the Down syndrome screening and do not worry too much.

What is the mom value for Down syndrome screening?

The MOM that appears in the Down screening result sheet is the multiple of the median value, which refers to how many times the test result of the pregnant woman's individual blood cell markers is higher than the median blood cell marker concentration of all normal pregnant women at that week of pregnancy during prenatal diagnosis. The key data are alpha-fetoprotein (AFP), human chorionic gonadotropin (β-hCG), free estriol (uE3) and inhibin A.

1. The general range of alpha fetal protein (AFP) is 0.7-2.5MOM. If it is higher than 2.5MOM, it is high risk;

2. The higher the chorionic gonadotropin, the lower the free estriol (uE3) (generally ≤0.25MOM) and the higher the inhibin A (Inhibin A), the higher the chance that the fetus will suffer from Down syndrome.

The doctor will also enter the above four items together with the pregnant woman's age, weight, gestational age, etc. into the computer to estimate the risk factors for the baby to have Down syndrome. If the probability indicated by the test result exceeds the normal standard value (1/270), the result is positive, indicating that the probability of the fetus being sick is relatively high and more detailed examinations are needed. However, the calculation methods of each hospital's outpatient department are not exactly the same, and the standards are also different. Some hospitals' outpatient standard values ​​are lower than 1/270, while others are lower than 1/380.

Is the result of Down syndrome screening reliable for determining the gender of a child?

Recently, the saying that "Down's syndrome screening report can determine the gender of a baby" has been circulating wildly on the Internet, and many netizens "pretend to know" and say that this method is very accurate. The actual testing standard is: look at the two standard values ​​in the Down syndrome screening report - the MOM value of HCG and the MOM value of AFP. The lower the MOM value of HCG (<0.4) and the higher the MOM value of AFP (>1), the more likely it is a boy; the higher the MOM value of HCG (>0.8) and the lower the MOM value of AFP (<1), the more likely it is a girl.

Is that really the case? Can Down's syndrome screening report really determine the gender of the baby?

Director Zhang and his friends who specialize in Down syndrome screening in the hospital carefully studied the latest 1,000 medical histories and found that the claim that Down syndrome screening reports can be used to identify the sex of the fetus is not scientifically proven or supported by data.