What causes no follicles?

The egg is composed of an oocyte in the ovarian cortex and many small and medium-sized oocytes around it. According to the changes in shape and function of the uterus during development, it can be divided into three stages: initial egg, developing egg and mature follicle. What is the reason for the lack of mature follicles?

1. Premature ovarian failure: The reason why some women’s follicles fail to grow is due to premature ovarian failure. Women may have normal menstruation in the early stage, and even have a history of pregnancy, but then have less menstrual blood, until they completely stop menstruating. In this case, the eggs in the uterus and ovaries have been exhausted, and it is impossible to use ovulation-inducing drugs to expand the uterus, or although there are original eggs, they have no response to gonadotropins.

2. Polycystic ovary syndrome: Polycystic ovary syndrome is one of the reasons why follicles fail to grow. Polycystic ovary syndrome is the most common cause of anovulation in women. The characteristics of its ovaries are that the ovarian volume is enlarged and there are many small eggs, but they cannot grow to perfection, so therapeutic drugs are needed to promote uterine development.

3. Endocrine function problems: Impairment of the hypothalamic-pituitary gland's regulation of the pituitary gland's function or abnormal metabolism of the uterus and ovaries themselves can cause poor uterine development, such as endocrine diseases such as hyperactivity of the adrenal glands and low thyroid hormone.

The number of eggs considered perfect is determined by one's physical condition, and everyone's condition is different. Generally speaking, the size of a normal mature follicle is 18-25mm.

Every month, women will release a perfect egg cell, and this perfect egg cell is usually more than 2b250m. But there are individual differences. Some people's eggs will be released when they grow to 15mm, and some people's eggs will be released when they grow to 25mm. You can check your specific situation by doing an ultrasound check once a period of time. Generally, a perfect egg will be discharged within one to two days, and the discharged egg can usually survive for 2 days.