The state of the endometrium actually reflects the health of the uterus. If there is low blood flow in the endometrium, it means that the health of the uterus is abnormal and needs to be adjusted appropriately. A general tip to improve low endometrial blood flow is to use vasodilator drugs, which can appropriately improve the blood circulation of the endometrium. Whether the endometrial blood flow is abundant is related to the thickness and shape of the endometrium. During the process of in vitro fertilization, paying attention to the endometrial blood flow has a certain significance for the success rate of embryo transplantation. If the intima is thin and blood flow is poor, appropriate treatment is required. Vasodilator drugs can be used to improve intima blood circulation. For example: small doses of aspirin, tadalafil, pentoxifylline, etc. can be taken orally or applied vaginally; some patients can also try mild scraping within the first two days of menstruation to stimulate the endometrium, stimulate the growth of endometrial capillaries, and stimulate the production of active substances on the endometrial surface such as cell activation factors, which can sometimes play a certain role in improving blood flow. Removing endometrial polyps and stimulating local scar tissue under hysteroscopy can also play a certain role in improving endometrial blood circulation. Treatments to improve the endometrium: 1. Drug treatment: For example, estrogen-progesterone replacement therapy. Appropriate amounts of estrogen and progesterone can increase the thickness of the endometrium to a certain extent. Sildenafil citrate is a 5-phosphodiesterase inhibitor that blocks the degradation of c-GMP and leads to vasodilation, including uterine vasodilation. Vaginal sildenafil has been used as a means to promote endometrial development by increasing uterine artery blood perfusion. The female uterus is also a muscular organ composed of smooth muscle, with the uterine artery and its rich vascular branches. Sildenafil can be used to directly act on the uterine smooth muscle and uterine artery smooth muscle, improve the blood supply to the endometrium, promote endometrial growth, improve the receptivity of the endometrium, and thus increase the success rate of transplantation. 2. Surgical treatment Suitable for thin endometrium caused by endometrial adhesion and damage. Hysteroscopy is the first choice, under which the damaged lesions can be clearly seen. Not only can the scope and type of adhesions be directly observed, but also the toughness of the adhesions can be determined. Membranous adhesions and fibromuscular adhesions can be separated under hysteroscopy or removed with surgical scissors; while dense connective tissue-like adhesions require electroresection under B-ultrasound monitoring. After the operation, an intrauterine contraceptive device is placed to prevent re-adhesion, and estrogen and progesterone are given to promote endometrial growth. Endometrial thickness is not the best prognostic indicator. If the endometrial low-speed blood flow is good, embryo transfer can be performed. Thin endometrium, endometrial scarring, and scanty menstruation are all important factors that affect pregnancy outcomes. |
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