If you want to do a paternity test, you can draw blood from the pregnant woman for the test. However, try not to use this testing method, as it will have more or less impact on the body of the fetus in your belly. In severe cases, it may lead to miscarriage. Therefore, you should directly draw blood from the baby for paternity testing. This will make the test results more accurate and avoid errors. The most commonly used method for identifying parent-child relationships is DNA typing. Human blood, hair, saliva, oral cells and bones can all be used for paternity testing, which is very convenient. A person has 23 pairs (46) of chromosomes. A pair of genes at the same position on the same pair of chromosomes is called alleles, usually one from the father and one from the mother. If the alleles at a certain DNA site are detected, one should be the same as the mother and the other should be the same as the father, otherwise there will be doubts. When using DNA for paternity testing, only a dozen to dozens of DNA sites need to be tested. If all are the same, the parent-child relationship can be determined. If more than 3 sites are different, the parent-child relationship can be ruled out. If one or two sites are different, the possibility of gene mutation should be considered, and some additional site tests should be performed for identification. The accuracy of DNA paternity testing in denying parent-child relationships is nearly 100%, and the accuracy of confirming parent-child relationships can reach 99.99%. DNA paternity testing is mainly determined by the following characteristics Somatic cell stability: The DNA in the blood, saliva, semen and various organ tissues of the same individual is consistent and remains unchanged throughout life for the same healthy person. This is the most basic premise. High individual specificity: The differences in genetic nature at the DNA molecular level among different individuals determine that when the same restriction enzyme digests genomic DNA, the number and length of allele fragments in one individual and another individual cannot be the same, thus producing DNA with individual specificity. In the 1980s, medical scientists pioneered the technology of using chromosome polymorphism to identify parent-child relationships. Chromosome polymorphism, also known as heteromorphism, refers to the slight variations in various chromosome morphologies commonly seen in the normal population (such as satellite enlargement, duplication or absence, variation in fluorescence intensity in the chromatin region, etc.). This polymorphism can be inherited. This technology uses its morphology to identify parent-child relationships, which relies on the subjective judgment of technicians and its accuracy is not satisfactory. |
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