What are the side effects of ovulation-stimulating injections?

Some female friends are very distressed that they have not been able to get pregnant. In this case, they will be very anxious and will think of getting an ovulation-stimulating injection. This method does have the effect of increasing the chance of pregnancy, but these drugs will cause many adverse reactions when injected into the body. Severe patients may even experience severe abdominal pain and gastrointestinal indigestion.

What are the side effects of ovulation-stimulating injections?

Pay attention to monitoring during medication

1. Measuring basal body temperature every day helps to understand ovarian ovulation;

2. Estrogen excretion measurement: After using this product for one week, collect urine or draw blood to measure estrogen every day. Use chorionic gonadotropin only 24 hours after the estrogen peak. If the estrogen value is too high, it is not advisable to give a large amount of HCG to avoid excessive stimulation of the ovaries.

3. Cervical mucus examination helps to understand the maturity of follicles or whether ovulation has occurred;

4. b-HCG immunoassay to detect early pregnancy; ⑥ For patients with high LH values, such as polycystic ovary syndrome, gonadotropin containing only FSH75 units should be used.

Adverse Reactions

1. When this product is used to stimulate ovulation, multiple follicles often develop at the same time, resulting in a high rate of multiple pregnancy, so immature newborns are also more common. Common adverse reactions include ovarian hyperstimulation syndrome (OHSS). In mild cases, there may be fullness or pain in the stomach and pelvis, abdominal pain, bloating, nausea, vomiting, diarrhea and other symptoms. The drug should be stopped immediately. Mild ovarian enlargement is common and disappears within 7 to 10 days. Moderate and severe OHSS may cause ascites and pleural effusion. If the ovaries enlarge to 10 cm in diameter, the patient should be hospitalized to avoid irreversible electrolyte imbalance or even death.

2. If the ovaries suddenly enlarge after stimulation, multiple follicles develop, accompanied by ovarian torsion or ovarian cyst rupture, there may even be blood accumulation in the abdominal cavity. Generally, symptoms may worsen 3 to 10 days after HCG injection to induce ovulation. The use of this product often increases the risk of arterial embolism. Some patients may have ascites, pleural effusion, arterial thromboembolism, and fever.

3. Ovarian enlargement and ovarian follicle rupture, leading to ovarian hyperstimulation syndrome such as peritoneal hemorrhage, pain, ascites, pleural reaction, oliguria, hypotension, and occasionally multiple births and gynecomastia in men.