Normal amount of progesterone in artificial cycle

Progesterone is an important support point needed in early pregnancy. It is not only closely related to the development of the chorionic villi and embryo, but also mainly helps the production of the placenta and the development of the fetus. The normal amount of progesterone in an artificial cycle requires a correct value. We need to understand progesterone first before we can make a judgment.

Progesterone is an important hormone that supports embryonic growth in early pregnancy. It, human chorionic gonadotropin (b-hcg) and estrogen are the three major hormones that promote embryonic growth. Progesterone is produced by the corpus luteum of the ovary in early pregnancy. After 8-10 weeks of pregnancy, with the production of the placenta, placental syncytiotrophoblast cells are produced. The progesterone level in maternal blood gradually increases as pregnancy progresses, reaching 312-624 nmol/l at full-term pregnancy. Therefore, the progesterone value is usually most significant in the first three months, and there is generally no need to pay attention to the progesterone value after the placenta is produced.

The progesterone value in early pregnancy generally has two units, divided into large units (ng/ml) and small units (nmol/l). The conversion relationship between the two is: 1ng/ml=3nmol/l. So after pregnancy, when looking at the progesterone level, the first thing to look at is whether it is a large unit or a small unit. Generally speaking, a progesterone value of >20ng/ml or >60nmol/l is considered normal.

The current consensus among experts is that as long as there is no vaginal bleeding in early pregnancy, there is no need to pay too much attention to the progesterone level. This is because progesterone is secreted in a pulsed manner throughout the day, and the values ​​will be different even if checked on the same day. So a low progesterone level in one test does not mean it is really low. It also depends on whether there is a fetal heartbeat or any signs of threatened abortion. If there are signs of threatened miscarriage, it is generally recommended to supplement progesterone regardless of the level of progesterone, because progesterone can also promote endometrial growth and promote embryo stability.