Symptoms of left lumbar nephritis in women

If a woman has nephritis, she must be careful in her life. Kidney disease has a great impact on human health. If you don't pay attention to good treatment, it will easily lead to chronic nephritis, which will have a greater impact on kidney function and may even easily cause kidney failure. Therefore, if kidney disease occurs, you must check in time to understand the specific cause and carry out good treatment. In daily life, you should pay attention to diet and take good care of yourself.

The first type: hypoproteinemia. Patients with nephritis lose a large amount of albumin in their bodies, and their serum albumin levels are mostly below 30g/l, so hypoproteinemia is very likely to occur at this time.

The second type: Hyperlipidemia nephritis patients have abnormal lipid metabolism, which leads to an increase in almost all lipoprotein components in the patient's plasma, with a significant increase in plasma total cholesterol and low-density lipoprotein cholesterol, and an increase in triglycerides and very low-density lipoprotein cholesterol.

The third type: massive proteinuria. The appearance of massive proteinuria symptoms is one of the reliable indicators for diagnosing nephritis.

The last type: severe edema. Patients with different types of nephritis, including nephritis, primary nephritis, etc., almost all nephritis patients may have varying degrees of edema clinically, and the edema is most obvious in the face, lower limbs, and scrotum. Edema in the body of patients with nephritis may last for weeks or months, or may occur throughout the disease with swelling coming and going. When patients encounter infection (especially streptococcal infection), edema often recurs or worsens, and even azotemia may occur.

The principles of treatment include removal of the predisposing factors, general treatment, treatment targeting the cause and pathogenesis, treatment of comorbidities and complications, and renal replacement therapy.

1. General treatment

This includes avoiding fatigue, eliminating triggers such as infection, avoiding contact with nephrotoxic drugs or poisons, adopting a healthy lifestyle (such as quitting smoking, exercising moderately, and controlling emotions), and a reasonable diet. During the acute phase, you should rest in bed and gradually increase your activity after the clinical symptoms improve. A low-salt diet (less than 3g per day) should be given during the acute phase. People with normal renal function do not need to limit protein intake, but in cases of azotemia, protein intake should be limited, and high-quality animal protein should be the main source. People with oliguria should limit their fluid intake.

Treatment targeting the immune pathogenesis often includes glucocorticoids and immunosuppressants. Blood purification treatments such as plasma exchange and immunoadsorption can effectively remove autoantibodies and antigen-antibody complexes from the body. Treatment targeting non-immune pathogenesis, including hypertension, hyperlipidemia, hyperglycemia, hyperuricemia, obesity, proteinuria, intrarenal hypercoagulable state, renin-angiotensin system activation, and oxidative stress. Renin-angiotensin system blockers, such as ACEI/ARB, are one of the most important therapeutic measures to slow the progression of kidney disease.

3. Treatment of comorbidities and complications

Patients with kidney disease often have multiple comorbidities, such as metabolic abnormalities, hypertension, coronary heart disease, heart failure and cirrhosis, which may aggravate the progression of kidney disease and should be actively treated.

Complications of kidney disease may involve various systems, such as infection, abnormal coagulation function, renal hypertension, renal anemia, renal osteodystrophy, water, electrolyte and acid-base imbalance, acute left heart failure, pulmonary edema and uremic encephalopathy, and should be treated actively.