What anti-inflammatory drugs should I take after vaginal tightening surgery?

In order to improve the quality of their sex life and increase their interest in sex life, some female friends go to some hospitals or beauty salons for vaginal tightening surgery, which may cause some inflammation and discomfort after the surgery. It is best to go to a specialized health hospital for this kind of private surgery to avoid infections in the urinary and reproductive systems. If you accidentally get infected, you can take levofloxacin hydrochloride to eliminate inflammation. Let’s take a look at its specific medicinal value and people who should not use it.

Levofloxacin hydrochloride is suitable for genitourinary system infections caused by sensitive bacteria, including simple and complicated urinary tract infections, bacterial prostatitis, Neisseria gonorrhoeae urethritis or cervicitis (including those caused by enzyme-producing strains). Respiratory tract infections, including acute exacerbations of bronchial infections and lung infections caused by sensitive Gram-negative bacilli. Gastrointestinal infections are caused by Shigella, Salmonella, enterotoxigenic Escherichia coli, Aeromonas hydrophila, Vibrio parahaemolyticus, etc. It can also treat systemic infections such as typhoid fever, bone and joint infections, skin and soft tissue infections and sepsis.

name

Chinese alias: Levofloxacin hydrochloride; (3S)-(-)-9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-;7H-pyrido[1,2,3-de]-[1,4]benzoxazine-6-carboxylic acid hydrochloride; Levofloxacin hydrochloride;

English Name:Levofloxacin Hydrochloride

English alias:LEVOFLOXACIN HCL; carboxylic acid monohydrochloride; LevofloxacinHydrochloride; (3S)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid hydrochloride:

Physical and chemical properties

Molecular formula:C18H21ClFN3O4

Boiling point: 571.5°C at 760 mmHg

Flash point: 299.4°C

Vapor pressure: 6.7E-14mmHg at 25°C

Pharmacological Action

It is the levorotatory form of ofloxacin, and its antibacterial activity is about twice that of ofloxacin. Its main mechanism of action is to inhibit the activity of bacterial DNA gyrase (bacterial topoisomerase II) and hinder bacterial DNA replication.

It has the characteristics of broad antibacterial spectrum and strong antibacterial effect. It has strong antibacterial activity against most Enterobacteriaceae, such as Escherichia coli, Klebsiella, Serratia, Proteus, Shigella, Salmonella, Citrobacter, Acinetobacter, as well as Gram-negative bacteria such as Pseudomonas aeruginosa, Haemophilus influenzae, and Neisseria gonorrhoeae. It also has good antibacterial effect on some methicillin-sensitive Staphylococci, Streptococcus pneumoniae, Streptococcus pyogenes, hemolytic Streptococcus and other Gram-positive bacteria and Legionella, Mycoplasma, Chlamydia, but its effect on anaerobic bacteria and enterococci is poor.

Indications

This product is suitable for the following mild and moderate infections caused by sensitive bacteria:

Respiratory system infections: acute bronchitis, acute exacerbation of chronic bronchitis, diffuse bronchiolitis, bronchiectasis with infection, pneumonia, tonsillitis (peritonsillar abscess);

Urinary tract infection: pyelonephritis, complicated urinary tract infection, etc.;

Reproductive system infection: acute prostatitis, acute epididymitis, intrauterine infection, adnexitis, pelvic inflammatory disease (metronidazole can be used in combination when anaerobic infection is suspected);

Skin and soft tissue infections: infectious impetigo, cellulitis, lymphangitis (adenitis), subcutaneous abscess, perianal abscess, etc.;

Intestinal infections: bacterial dysentery, infectious enteritis, salmonella enteritis, typhoid and paratyphoid;

Sepsis, neutropenia and various infections in immunocompromised patients;

Other infections: mastitis, trauma, burns and post-operative wound infection, abdominal infection (use metronidazole when necessary), cholecystitis, cholangitis, bone and joint infection and ENT infection, etc.

Dosage

The oral absorption rate is almost 100%. Common dosage for adults:

1. Bronchial infection, lung infection: 0.2g at a time, twice a day, or 0.1g at a time, 3 times a day, the course of treatment is 7 to 14 days.

2. Acute simple lower urinary tract infection: 0.1g at a time, twice a day, for 5 to 7 days; complicated urinary tract infection: 0.2g at a time, twice a day, or 0.1g at a time, 3 times a day, for 10 to 14 days.

3. Bacterial prostatitis: 0.2g at a time, twice a day, for 6 weeks.

The usual dosage for adults is 0.3-0.4 g per day, taken in 2-3 times. If the infection is severe or the patient is less sensitive to the pathogen, such as Pseudomonas aeruginosa and other Pseudomonas bacterial infections, the therapeutic dose can be increased to 0.6 g per day, taken in 3 times.

Adverse Reactions

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During medication, you may experience symptoms such as nausea, vomiting, abdominal discomfort, diarrhea, lack of appetite, abdominal pain, bloating, insomnia, dizziness, headache, and other neurological symptoms, as well as rash, itching, and other symptoms. Transient liver function abnormalities may also occur, such as increased serum aminotransferase and increased serum total bilirubin. The incidence of the above adverse reactions is between 0.1% and 5%. Occasionally, there will be an increase in blood urea nitrogen, fatigue, fever, palpitations, abnormal taste, etc., which are generally tolerated and disappear quickly after the treatment.

[Contraindications] It is contraindicated for patients who are allergic to quinolones, pregnant or lactating women, and patients under 18 years old.

side effect

1. When used simultaneously with non-steroidal anti-inflammatory analgesics (such as aspirin, ibuprofen, acetaminophen, etc.), convulsions may be induced.

2. When used simultaneously with oral hypoglycemic drugs, it may cause blood sugar disorders, including hyperglycemia and hypoglycemia.

3. Sometimes nausea, vomiting, abdominal discomfort, diarrhea, abdominal pain, indigestion, etc. may occur;

4. Sometimes allergic reactions may occur, such as: occasional edema, urticaria, fever, photosensitivity, and sometimes rash, itching, erythema and other symptoms;

5. Occasionally there may be nervous system reactions: such as tremors, numbness, visual abnormalities, tinnitus, hallucinations, drowsiness, and sometimes insomnia, dizziness, headaches, etc.

6. Kidney: Increased urea nitrogen in the blood may occur occasionally.

7. It can cause liver function abnormalities, such as transient increase in blood aminotransferase and increase in serum total bilirubin.

8. Anemia, leukopenia, thrombocytopenia and eosinophilia may sometimes occur.

The incidence of the above-mentioned adverse reactions is between 0.1% and 5%, which are generally tolerated and disappear quickly after the treatment. If any abnormality is found, you should observe carefully and stop taking the medication and take appropriate measures if necessary.