What is the normal thickness of the endometrium?

Many female friends who are preparing to conceive feel that there are problems with their endometrium, making it difficult for them to get pregnant. This phenomenon troubles many couples and also affects many families. The following article will introduce to you the approximate thickness of the normal endometrium to popularize relevant knowledge.

In the early stage of hyperplasia, the endometrium appears as a thin echo line, about 4-6 mm thick. In the middle stage of hyperplasia, the endometrium gradually shows three strong echo lines, and the low echo area in between is two layers of functional endometrium with a thickness of about 8-10mm. In the late stage of hyperplasia, the three lines and two zones are more clearly visible, and the thickness of the endometrium increases to about 9-10 mm.

Secretory phase:

After the corpus luteum is formed, the endometrium shows a secretory reaction under the action of progesterone. The secretory phase is also divided into three stages: early, middle and late.

Early secretory phase:

Day 15-19 of the menstrual cycle. During this stage, the endometrial glands are longer and more curved. Small vesicles containing glycogen begin to appear under the nuclei of glandular epithelial cells, called subnuclear vacuoles, which are histological features of the early stage of secretion.

Mid-secretory phase:

Day 20-23 of the menstrual cycle. The inner membrane is thicker and more serrated than before. The apical cell membrane of the secretory epithelial cells in the gland ruptures, and the glycogen in the cells is discharged into the glandular cavity, which is called apocrine secretion. During this period, the interstitial tissue is highly edematous and loose, and the spiral arterioles proliferate and curl.

Late secretory phase:

Day 24-28 of the menstrual cycle. This period is the pre-menstrual period. The endometrium becomes thickened and spongy. The openings of the endometrial glands face the organ cavity, with secretions such as glycogen overflowing, the stroma becoming looser and more edematous, and the stroma under the surface epithelial cells differentiate into hypertrophic decidual-like cells. During this stage, the spiral arterioles grow rapidly beyond the thickness of the intima, become more curved, and the vascular lumen expands. In the late secretory phase, the thickness of the endometrium is about 5 to 6 mm.

In the above article, we learned about the normal thickness of the endometrium. Only with a normal endometrium can the egg implant successfully. Generally speaking, if the endometrium is too thick, friends can seek treatment to get pregnant successfully.