Because the urethra is the only way for urination, it is often invaded by bacteria or other dirt in the urine, which can easily cause inflammation. People with low immunity should pay attention to prevention. Of course, there are many causes of urethritis, and some urinary system diseases also have the chance to cause it, so once any abnormality is found, it must be treated in time. So, how to treat female urinary tract infection? Urinary tract infection in non-pregnant women (1) A three-day therapy is recommended for the treatment of acute simple cystitis, which consists of taking oral co-sulfamethoxazole, ofloxacin, or levofloxacin. Because the efficacy of single-dose therapy is not as good as the three-day therapy, it is no longer recommended. In areas where the resistance rate of pathogens to sulfamethoxazole is as high as 10% to 20%, nitrofurantoin can be used for treatment. (2) For the treatment of acute simple pyelonephritis, it is recommended to use antibiotics for 14 days. For patients with mild acute pyelonephritis, the course of treatment can be shortened to 7 days using high-efficiency antibiotics. For mild cases, oral quinolones can be used for treatment. If the pathogen is sensitive to trimethoprim-sulfamethoxazole, this drug can also be taken orally. If the causative bacteria are gram-positive, treatment can be with amoxicillin alone or amoxicillin/clavulanate potassium. For severe cases or those who cannot take oral medications, they should be hospitalized and treated with intravenous quinolones or broad-spectrum cephalosporin antibiotics. For those who are resistant to β-lactam antibiotics and quinolone antibiotics, aztreonam can be used for treatment. If the pathogen is a Gram-positive coccus, ampicillin/sulbactam sodium can be used, and combined medication can be used if necessary. If the condition improves, sensitive antibiotics can be selected for oral treatment based on the urine culture results. Regimen adjustment and follow-up are very important during medication. Urine culture should be performed every 1 to 2 weeks to observe whether the urine bacteria turns negative. Quantitative urine bacterial culture should be performed at the end of the treatment and 2 and 6 weeks after stopping the medication. It is best to review it once a month thereafter. (3) Complicated urinary tract infection The treatment plan for complicated urinary tract infection depends on the severity of the disease. In addition to antimicrobial treatment, it is also necessary to simultaneously address anatomical and functional abnormalities of the urinary system and treat other underlying diseases. If necessary, nutritional support therapy is also required. If the condition is severe, hospitalization is usually required. First of all, the underlying diseases such as diabetes and urinary tract infarction should be controlled promptly and effectively. If necessary, joint treatment with relevant professional doctors such as endocrinologists is needed. Otherwise, it is difficult to cure the disease with antibiotics alone. Second, treat with broad-spectrum intravenous antibiotics empirically. During the medication period, the treatment plan should be adjusted in time according to changes in the condition and/or the results of bacterial drug sensitivity tests. Some patients may need combination therapy, and the course of treatment should be at least 10 to 14 days. |
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